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These remained unchanged over 3 years and he retained excellent 6\/7.5 visual acuity bilaterally. We hypothesised the mechanism of bilateral segmental infarction of the optic nerve head to be caused by the hypercoagulable and hypovolaemic state, in addition to pre-existing vascular disease and hypertension. This case highlights the importance of including optic nerve examination in the management plan of SCLS, particularly in individuals with underlying vascular risk factors.<\/jats:p>","DOI":"10.1136\/bcr-2021-242847","type":"journal-article","created":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T12:29:10Z","timestamp":1620131350000},"page":"e242847","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Bilateral simultaneous non-arteritic ischaemic optic neuropathy: a rare complication of idiopathic systemic capillary leak syndrome (SCLS)"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8319-7889","authenticated-orcid":false,"given":"Yan Ning","family":"Neo","sequence":"first","affiliation":[{"name":"Ophthalmology Department, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manvi","family":"Sobti","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hadi","family":"Zambarakji","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,5,4]]},"reference":[{"key":"2025082713070071000_14.5.e242847.1","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1080\/14779072.2018.1456920","article-title":"Recognition and management of idiopathic systemic capillary leak syndrome: an evidence-based review","volume":"16","author":"Baloch","year":"2018","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"2025082713070071000_14.5.e242847.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(97)00272-6"},{"key":"2025082713070071000_14.5.e242847.3","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/S0161-6420(87)33350-0","article-title":"Anterior ischemic optic neuropathy. 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