{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T00:41:41Z","timestamp":1768696901046,"version":"3.49.0"},"reference-count":8,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,7,12]]},"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:p>Systemic sclerosis (SSc) is a rare connective tissue disorder with a complex pathogenesis involving vascular dysfunction, small vessel proliferation as well as alterations of innate and adaptive immunity. Gastrointestinal (GI) involvement in SSc is almost universal and affects nearly 90% of the patients. Of all the GI manifestations, 30%\u201375% are oesophageal abnormalities, including gastro-oesophageal reflux disease, reflux oesophagitis and Barret\u2019s oesophagus. The incidence of gastric manifestations is about 22% with a common presentation of gastric antral vascular ectasia (GAVE). However, autoimmune atrophic gastritis (AIG) is not a known manifestation of SSc. Our case has a unique presentation of the coexistence of GAVE and AIG. We have conducted a thorough literature review to study a possible association of AIG and SSc and understand the pathology of SSc.<\/jats:p>","DOI":"10.1136\/bcr-2021-242851","type":"journal-article","created":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T12:55:39Z","timestamp":1628859339000},"page":"e242851","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Autoimmune atrophic gastritis in systemic sclerosis"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7033-5928","authenticated-orcid":false,"given":"Deepti","family":"Avasthi","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Mercy St Vincent Medical Center, Toledo, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Pathology, Mercy Saint Vincent Medical Center, Toledo, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leela Krishna Vamsee","family":"Miriyala","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Mercy St Vincent Medical Center, Toledo, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salil","family":"Avasthi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Mercy St Vincent Medical Center, Toledo, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,8,13]]},"reference":[{"key":"2025082710352924000_14.8.e242851.1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200011)43:11<2437::AID-ANR10>3.0.CO;2-U"},{"key":"2025082710352924000_14.8.e242851.2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.4.5785.451"},{"key":"2025082710352924000_14.8.e242851.3","first-page":"5095","article-title":"Upper gastrointestinal involvement in systemic sclerosis: findings in a real-life setting","volume":"18","author":"Petcu","year":"2019","journal-title":"Exp Ther Med"},{"key":"2025082710352924000_14.8.e242851.4","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-12-1067"},{"key":"2025082710352924000_14.8.e242851.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2012.02.018"},{"key":"2025082710352924000_14.8.e242851.6","doi-asserted-by":"crossref","first-page":"162","DOI":"10.5114\/reum.2020.96655","article-title":"Haematological abnormalities in systemic sclerosis","volume":"58","author":"Wielosz","year":"2020","journal-title":"Reumatologia"},{"key":"2025082710352924000_14.8.e242851.7","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1097\/RHU.0000000000000686","article-title":"Evaluation of vitamin B12 deficiency and associated factors in patients with systemic sclerosis","volume":"24","author":"Tas Kilic","year":"2018","journal-title":"J Clin Rheumatol"},{"key":"2025082710352924000_14.8.e242851.8","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2005.090514"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-242851","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:35:36Z","timestamp":1756316136000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-242851"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":8,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2021,8,13]]},"published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1136\/bcr-2021-242851"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-242851","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8]]}}}