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More than 3\u2009years of therapy with amitriptyline, gabapentin, pregabalin and various grade II and III opioids was ineffective or showed intolerable side effects. The administration of tetrahydrocannabinol and cannabidiol as an oromucosal spray in a 1:1 ratio improved the pain situation and quality of life quickly and permanently. The encouraging results in the present case may suggest that treatment with medical cannabis should be considered in similar cases when standard therapies are insufficient.<\/jats:p>","DOI":"10.1136\/bcr-2021-243072","type":"journal-article","created":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T12:20:59Z","timestamp":1625574059000},"page":"e243072","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Tetrahydrocannabinol and cannabidiol as an oromucosal spray in a 1:1 ratio: a therapeutic option for patients with central post-stroke pain syndrome?"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1880-0033","authenticated-orcid":false,"given":"Ulrich","family":"Moser","sequence":"first","affiliation":[{"name":"Bayerische \u00c4rztekammer, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,7,6]]},"reference":[{"key":"2025082703101739000_14.7.e243072.1","first-page":"1","article-title":"Central pain mimicking trigeminal neuralgia as a result of lateral medullary ischemic stroke","volume":"2019","author":"Ravichandran","year":"2019","journal-title":"Case Rep Neurol Med"},{"key":"2025082703101739000_14.7.e243072.2","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-020-01388-w"},{"key":"2025082703101739000_14.7.e243072.3","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s10194-011-0305-9","article-title":"Wallenberg's syndrome and symptomatic trigeminal neuralgia","volume":"12","author":"Ord\u00e1s","year":"2011","journal-title":"J Headache Pain"},{"key":"2025082703101739000_14.7.e243072.4","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.pmrj.2016.05.015","article-title":"Demystifying poststroke pain: from etiology to treatment","volume":"9","author":"Treister","year":"2017","journal-title":"Pm R"},{"key":"2025082703101739000_14.7.e243072.5","doi-asserted-by":"crossref","first-page":"207","DOI":"10.31887\/DCNS.2020.22.3\/blutz","article-title":"Neurobiology of cannabinoid receptor signaling","volume":"22","author":"Lutz","year":"2020","journal-title":"Dialogues Clin Neurosci"},{"key":"2025082703101739000_14.7.e243072.6","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1213\/ANE.0000000000002110","article-title":"Selective cannabinoids for chronic neuropathic pain: a systematic review and meta-analysis","volume":"125","author":"Meng","year":"2017","journal-title":"Anesth Analg"},{"key":"2025082703101739000_14.7.e243072.7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.2011.03970.x"},{"key":"2025082703101739000_14.7.e243072.8","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1007\/s00482-011-1142-0","article-title":"Deutscher Schmerzfragebogen (DSF) und standardisierte Dokumentation MIT KEDOQ-Schmerz. 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