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We aim to characterise the common features, the spectrum of disease within a single family and discuss a potential role for low-dose dexamethasone in the management of ventilator-dependent patients with IPS.<\/jats:p>","DOI":"10.1136\/bcr-2021-243348","type":"journal-article","created":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T12:12:21Z","timestamp":1629461541000},"page":"e243348","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Experience of low-dose dexamethasone use in the respiratory management of ichthyosis prematurity syndrome"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2503-4886","authenticated-orcid":false,"given":"Davina","family":"Henderson","sequence":"first","affiliation":[{"name":"Department of Neonatology, Rotunda Hospital Neonatal Unit, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire A","family":"Murphy","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Rotunda Hospital Neonatal Unit, Dublin, Ireland"},{"name":"Department of Paediatrics, Royal College of Surgeons in Ireland, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"O'Dea","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Rotunda Hospital Neonatal Unit, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2960-7653","authenticated-orcid":false,"given":"Michael A","family":"Boyle","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Rotunda Hospital Neonatal Unit, Dublin, Ireland"},{"name":"Department of Paediatrics, Royal College of Surgeons in Ireland, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,8,20]]},"reference":[{"key":"2025082707294002000_14.8.e243348.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2009.06.021"},{"key":"2025082707294002000_14.8.e243348.2","doi-asserted-by":"crossref","DOI":"10.1186\/1756-0500-4-90","article-title":"Fatp4 missense and nonsense mutations cause similar features in ichthyosis prematurity syndrome","volume":"4","author":"Sobol","year":"2011","journal-title":"BMC Res Notes"},{"key":"2025082707294002000_14.8.e243348.3","doi-asserted-by":"crossref","unstructured":"Salda\u00f1a-Garc\u00eda N , Espinosa-Fern\u00e1ndez MG , Serrano-Mart\u00edn MDM . 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