{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T21:41:20Z","timestamp":1773092480896,"version":"3.50.1"},"reference-count":10,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,9,2]]},"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:p>Mucormycosis is a very commonly encountered disease in the sinonasal region in patients with diabetes and immunocompromised status specially in the northern part of the Indian continent. Due to its fulminant nature and involvement in the rhino-orbital-cerebral region, prognosis is poor even after extensive debridement and amphotericin-B therapy. We present a case with diagnosis of sarcoidosis being treated with systemic steroids who developed sudden-onset ptosis and left lateral rectus palsy. On radiological evaluation with MRI, a heterogenously peripherally enhancing lesion was seen in the nasopharynx suggestive of nasopharyngeal abscess. The patient was taken up for emergency surgery; a necrotic lesion with destruction of sphenoid bone, pterygoids and clivus was seen originating in the nasopharynx. The lesion on fungal staining came out to be broad aseptate hyphae suggestive of mucormycosis.<\/jats:p>","DOI":"10.1136\/bcr-2021-243530","type":"journal-article","created":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T12:45:26Z","timestamp":1631796326000},"page":"e243530","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Fungal central skull-base osteomyelitis: atypical presentation and management issues"],"prefix":"10.1136","volume":"14","author":[{"given":"Sanjeev","family":"Yadav","sequence":"first","affiliation":[{"name":"Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajeev","family":"Kumar","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rakesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5590-9279","authenticated-orcid":false,"given":"Prem","family":"Sagar","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,9,16]]},"reference":[{"key":"2025082623020749000_14.9.e243530.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2007.03.001"},{"key":"2025082623020749000_14.9.e243530.2","article-title":"Clinical characteristics of patients in a case control study of sarcoidosis","volume":"2001","author":"Baughman","year":"1885","journal-title":"Am J Respir Crit Care Med"},{"key":"2025082623020749000_14.9.e243530.3","first-page":"209","article-title":"Diagnostic value of peripheral lymph node biopsy in sarcoidosis: a report of 67 cases","volume":"14","author":"Yanardag","year":"2007","journal-title":"Can Respir J"},{"key":"2025082623020749000_14.9.e243530.4","doi-asserted-by":"publisher","DOI":"10.2500\/105065800782102753"},{"key":"2025082623020749000_14.9.e243530.5","doi-asserted-by":"crossref","DOI":"10.4103\/0974-777X.56256","article-title":"The rise of an opportunistic infection called \"Invasive Zygomycosis\"","volume":"1","author":"Waness","year":"2009","journal-title":"J Glob Infect Dis"},{"key":"2025082623020749000_14.9.e243530.6","doi-asserted-by":"crossref","first-page":"S93","DOI":"10.1093\/mmy\/myx101","article-title":"Challenges in the diagnosis and treatment of mucormycosis","volume":"56","author":"Skiada","year":"2018","journal-title":"Med Mycol"},{"key":"2025082623020749000_14.9.e243530.7","doi-asserted-by":"publisher","DOI":"10.1177\/019459988008800215"},{"key":"2025082623020749000_14.9.e243530.8","first-page":"1","article-title":"Carotid artery occlusion by rhinoorbitocerebral mucormycosis","volume":"2012","author":"Al-Otaibi","year":"2012","journal-title":"Case Rep Surg"},{"key":"2025082623020749000_14.9.e243530.9","first-page":"20150448","article-title":"Angioinvasive rhinocerebral mucormycosis with complete unilateral thrombosis of internal carotid artery\u2014case report and review of literature","volume":"1","author":"Patil","year":"2016","journal-title":"BJR| case reports"},{"key":"2025082623020749000_14.9.e243530.10","doi-asserted-by":"crossref","first-page":"e405","DOI":"10.1016\/S1473-3099(19)30312-3","article-title":"Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of medical mycology in cooperation with the mycoses Study Group education and research Consortium","volume":"19","author":"Cornely","year":"2019","journal-title":"Lancet Infect Dis"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-243530","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T06:02:20Z","timestamp":1756274540000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-243530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":10,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2021,9,16]]},"published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1136\/bcr-2021-243530"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-243530","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9]]}}}