{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:32:08Z","timestamp":1791815528973,"version":"4.3.4"},"reference-count":15,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,7,6]]},"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:p>A 72-year-old woman with a history of removal of a right hemimandibular keratocyst 10 years ago was referred to our attention for a large swelling of the right cheek. The orthopantomography and the CT scan showed a huge osteolytic area of the right mandibular ramus and angle. The patient\u2019s refusal to resection and reconstruction with a free flap pushed us towards a conservative treatment. The high probability of a iatrogenic mandibular fracture during and after surgery required the design of a customised titanium plate to be preliminary placed through cervical incision along the posterior border of the mandible. The patient successfully underwent the surgical positioning of the customised plate and subsequent removal of the keratocyst. She was discharged fit and well 5\u2009days after surgery. She did not experience any infections, pathological fractures or relapse in the 6-month follow-up.<\/jats:p>","DOI":"10.1136\/bcr-2021-243576","type":"journal-article","created":{"date-parts":[[2021,7,15]],"date-time":"2021-07-15T12:37:15Z","timestamp":1626352635000},"page":"e243576","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Placement of a customised load-bearing titanium plate for prevention of iatrogenic mandibular fracture in surgical removal of odontogenic keratocyst recurrence"],"prefix":"10.1136","volume":"14","author":[{"given":"Andrea","family":"Castellani","sequence":"first","affiliation":[{"name":"Maxillo-facial Unit, ASST Spedali Civili di Brescia, Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Maxillo-facial Unit, ASST Spedali Civili di Brescia, Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Daleffe","sequence":"additional","affiliation":[{"name":"Maxillo-facial Unit, ASST Spedali Civili di Brescia, Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6184-8767","authenticated-orcid":false,"given":"Karim","family":"Tewfik","sequence":"additional","affiliation":[{"name":"Head&Neck Department, IRCCS Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy"},{"name":"Pediatric Maxillo-facial Unit, ASST Spedali Civili di Brescia, Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,7,15]]},"reference":[{"key":"2025082803250348000_14.7.e243576.1","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.jcms.2009.10.006","article-title":"Management of odontogenic keratocysts of the jaws: a ten-year experience with 120 consecutive lesions","volume":"38","author":"Pitak-Arnnop","year":"2010","journal-title":"J Craniomaxillofac Surg"},{"key":"2025082803250348000_14.7.e243576.2","doi-asserted-by":"crossref","first-page":"e411","DOI":"10.1097\/SCS.0000000000005397","article-title":"Solitary plasmacytoma of the mandible: early diagnosis and surgical management","volume":"30","author":"Rullo","year":"2019","journal-title":"J Craniofac Surg"},{"key":"2025082803250348000_14.7.e243576.3","first-page":"00056","article-title":"Surgical management of the odontogenic keratocyst: a 20-year experience","volume":"2:S0901-5027(21","author":"Mohanty","year":"2021","journal-title":"Int J Oral Maxillofac Surg"},{"key":"2025082803250348000_14.7.e243576.4","doi-asserted-by":"crossref","first-page":"26","DOI":"10.23736\/S2724-6329.20.04422-2","article-title":"Surgical conservative approach of odontogenic keratocyst tumor of the jaws","volume":"70","author":"Laino","year":"2021","journal-title":"Minerva Dent Oral Sci"},{"key":"2025082803250348000_14.7.e243576.5","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1016\/j.ijom.2016.02.002","article-title":"Results of the treatment of keratocystic odontogenic tumours using enucleation and treatment of the residual bony defect with Carnoy's solution","volume":"45","author":"Leung","year":"2016","journal-title":"Int J Oral Maxillofac Surg"},{"key":"2025082803250348000_14.7.e243576.6","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1097\/MOO.0000000000000269","article-title":"Recent trends in the treatment of benign odontogenic tumors","volume":"24","author":"Covello","year":"2016","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"2025082803250348000_14.7.e243576.7","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph16245139","article-title":"Reliability of a virtual Prosthodontic project realized through a 2D and 3D photographic acquisition: an experimental study on the accuracy of different digital systems","volume":"16","author":"Lavorgna","year":"2019","journal-title":"Int J Environ Res Public Health"},{"key":"2025082803250348000_14.7.e243576.8","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1097\/01.PRS.0000097719.69616.29","article-title":"Segmental mandibulectomy and immediate free fibula osteoseptocutaneous flap reconstruction with endosteal implants: an ideal treatment method for mandibular ameloblastoma","volume":"113","author":"Chana","year":"2004","journal-title":"Plast Reconstr Surg"},{"key":"2025082803250348000_14.7.e243576.9","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1097\/00001665-200411000-00022","article-title":"Free fibula flap mandible reconstruction in benign mandibular lesions","volume":"15","author":"Bilkay","year":"2004","journal-title":"J Craniofac Surg"},{"key":"2025082803250348000_14.7.e243576.10","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1016\/j.jcms.2015.06.003","article-title":"Design and optimization of the fixing plate for customized mandible implants","volume":"43","author":"Qin","year":"2015","journal-title":"J Craniomaxillofac Surg"},{"key":"2025082803250348000_14.7.e243576.11","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1055\/s-0036-1597585","article-title":"A case of an extensive keratocystic odontogenic tumor in the mandible reconstructed with a custom-made total joint prosthesis","volume":"11","author":"Farzad","year":"2018","journal-title":"Craniomaxillofac Trauma Reconstr"},{"key":"2025082803250348000_14.7.e243576.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2007.09.176"},{"key":"2025082803250348000_14.7.e243576.13","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.ijom.2013.02.004","article-title":"Extra-platysma fixation of bisphosphonate-related mandibular fractures: a suggested technical solution","volume":"42","author":"Biglioli","year":"2013","journal-title":"Int J Oral Maxillofac Surg"},{"key":"2025082803250348000_14.7.e243576.14","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.bjps.2020.11.040","article-title":"Inferior alveolar nerve reconstruction in extensive mandibular resection: technical notes","volume":"74","author":"Manfuso","year":"2021","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"2025082803250348000_14.7.e243576.15","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s12663-015-0828-8","article-title":"Regeneration of a compromized masticatory unit in a large mandibular defect caused by a huge solitary bone cyst: a case report and review of the regenerative literature","volume":"15","author":"Muhammad","year":"2016","journal-title":"J Maxillofac Oral Surg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-243576","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:25:15Z","timestamp":1756376715000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-243576"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":15,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2021,7,15]]},"published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1136\/bcr-2021-243576"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-243576","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}