{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T22:40:11Z","timestamp":1772491211290,"version":"3.50.1"},"reference-count":12,"publisher":"BMJ","issue":"6","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/bmj.com\/coronavirus\/usage"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,5,1]]},"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:p>A 22-year-old woman was referred with exertional dyspnoea and chest tightness 3\u2009weeks following a diagnosis of COVID-19. Evaluation revealed a resting sinus tachycardia and criteria for postural orthostatic tachycardia syndrome were met. After non-pharmacological interventions failed to yield symptomatic improvement, ivabradine was commenced. This intervention was followed by a substantial improvement in the patient\u2019s exercise tolerance and energy levels and an objective reduction in supine and standing heart rate.<\/jats:p>","DOI":"10.1136\/bcr-2021-243585","type":"journal-article","created":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T12:40:37Z","timestamp":1623674437000},"page":"e243585","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":23,"title":["COVID-19-induced postural orthostatic tachycardia syndrome treated with ivabradine"],"prefix":"10.1136","volume":"14","author":[{"given":"Jenna Stephanie","family":"O'Sullivan","sequence":"first","affiliation":[{"name":"Cardiology, Mercy University Hospital, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Lyne","sequence":"additional","affiliation":[{"name":"Tower Medical Centre, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl J","family":"Vaughan","sequence":"additional","affiliation":[{"name":"Cardiology, Mercy University Hospital, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,6,14]]},"reference":[{"key":"2025082709543057000_14.6.e243585.1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2006.055046"},{"key":"2025082709543057000_14.6.e243585.2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.144501"},{"key":"2025082709543057000_14.6.e243585.3","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.1_Part_1.132"},{"key":"2025082709543057000_14.6.e243585.4","doi-asserted-by":"publisher","DOI":"10.4065\/82.3.308"},{"key":"2025082709543057000_14.6.e243585.5","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1111\/joim.12895","article-title":"The face of postural tachycardia syndrome - insights from a large cross-sectional online community-based survey","volume":"286","author":"Shaw","year":"2019","journal-title":"J Intern Med"},{"key":"2025082709543057000_14.6.e243585.6","doi-asserted-by":"crossref","DOI":"10.1017\/S0317167100004108","article-title":"Autonomic dysfunction in recovered severe acute respiratory syndrome patients","volume":"32","author":"Lo","year":"2005","journal-title":"Can J Neurol Sci"},{"key":"2025082709543057000_14.6.e243585.7","doi-asserted-by":"crossref","first-page":"571-573","DOI":"10.1007\/s10286-020-00733-x","article-title":"Acute hyperhidrosis and postural tachycardia in a COVID-19 patient","volume":"30","author":"Umapathi","year":"2020","journal-title":"Clin Auton Res"},{"key":"2025082709543057000_14.6.e243585.8","doi-asserted-by":"crossref","first-page":"e1060","DOI":"10.1212\/WNL.0000000000009937","article-title":"Neurologic manifestations in hospitalized patients with COVID-19: the ALBACOVID registry","volume":"95","author":"Romero-S\u00e1nchez","year":"2020","journal-title":"Neurology"},{"key":"2025082709543057000_14.6.e243585.9","unstructured":"Kings College London . COVID symptom study. how long does COVID-19 last? 2020. Available: https:\/\/covid19.joinzoe.com\/post\/covid-long-term?fbclid=IwAR1RxIcmmdL-EFjh_aI-"},{"key":"2025082709543057000_14.6.e243585.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.03.029"},{"key":"2025082709543057000_14.6.e243585.11","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.jacc.2020.12.029","article-title":"Randomized trial of ivabradine in patients with Hyperadrenergic postural orthostatic tachycardia syndrome","volume":"77","author":"Taub","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"2025082709543057000_14.6.e243585.12","unstructured":"Health Service Executive Ireland . Health service employment report December 2020; 2020: 46. https:\/\/www.hse.ie\/eng\/staff\/resources\/our-workforce\/workforce-reporting\/health-service-employment-report-december-2020.pdf [Accessed 14 Feb 2021]."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-243585","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:54:41Z","timestamp":1756313681000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-243585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":12,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,6,14]]},"published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1136\/bcr-2021-243585"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-243585","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6]]}}}