{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T21:27:39Z","timestamp":1760909259136,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"8","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/bmj.com\/coronavirus\/usage"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,8,5]]},"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:p>A COVID-19 infection predisposes the infected person to thrombotic events. Myocardial infarction, acute limb ischaemia, mesenteric artery thrombosis and pulmonary embolism are all well-documented complications of this infection. Here we describe a pregnant patient who presented with obstructed labour with asymptomatic COVID-19 infection and developed ascites during the postoperative period. Further work-up of the patient revealed portal hypertension due to portal vein thrombosis (PVT). As the patient was healthy before this index pregnancy, a causative link between COVID-19 and PVT cannot be ruled out. Her COVID-19 infection progressed to a moderate disease. She was managed with steroids and appropriate antibiotics for secondary bacterial peritonitis. She was finally discharged after 2.5 months of multidisciplinary treatment. This is a case of a survivor of complications due to pregnancy, COVID-19 and extrahepatic portal vein obstruction.<\/jats:p>","DOI":"10.1136\/bcr-2021-243697","type":"journal-article","created":{"date-parts":[[2021,8,12]],"date-time":"2021-08-12T12:08:09Z","timestamp":1628770089000},"page":"e243697","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Extrahepatic portal vein thrombosis in a pregnant patient with COVID-19: a rare thrombotic event survivor"],"prefix":"10.1136","volume":"14","author":[{"given":"Mukta","family":"Agarwal","sequence":"first","affiliation":[{"name":"Obstetrics and Gynaecology, AIIMS Patna, Patna, Bihar, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Smita","family":"Singh","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, AIIMS Patna, Patna, Bihar, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Upasna","family":"Sinha","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, AIIMS Patna, Patna, Bihar, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Divendu","family":"Bhushan","sequence":"additional","affiliation":[{"name":"General Medicine, All India Institute of Medical Sciences Patna, Patna, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,8,12]]},"reference":[{"key":"2025082708375610000_14.8.e243697.1","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.tjog.2013.11.012","article-title":"Extrahepatic portal-vein obstruction in pregnancy","volume":"54","author":"Subbaiah","year":"2015","journal-title":"Taiwan J Obstet Gynecol"},{"key":"2025082708375610000_14.8.e243697.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"2025082708375610000_14.8.e243697.3","doi-asserted-by":"crossref","first-page":"142","DOI":"10.3389\/fped.2018.00142","article-title":"The role of inflammation in venous thromboembolism","volume":"6","author":"Branchford","year":"2018","journal-title":"Front Pediatr"},{"key":"2025082708375610000_14.8.e243697.4","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e31819bceb1"},{"key":"2025082708375610000_14.8.e243697.5","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1447-0756.2010.01407.x","article-title":"Extra hepatic portal vein obstruction and pregnancy outcome: largest reported experience","volume":"37","author":"Aggarwal","year":"2011","journal-title":"J Obstet Gynaecol Res"},{"key":"2025082708375610000_14.8.e243697.6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0020-7292(00)00263-0","article-title":"Non-Cirrhotic portal hypertension in pregnancy","volume":"72","author":"Aggarwal","year":"2001","journal-title":"Int J Gynaecol Obstet"},{"key":"2025082708375610000_14.8.e243697.7","unstructured":"Prime PubMed | maternal-fetal outcome in pregnancies complicated with non-cirrhotic portal hypertension: experience from a tertiary centre in South India. Available: https:\/\/www.unboundmedicine.com\/medline\/citation\/32588317\/Maternal-fetal_outcome_in_pregnancies_complicated_with_non-cirrhotic_portal_hypertension:_experience_from_a_Tertiary_Centre_in_South_India [Accessed 13 Apr 2021]."},{"key":"2025082708375610000_14.8.e243697.8","first-page":"676","article-title":"Is pregnancy safe with extrahepatic portal vein obstruction? an analysis","volume":"53","author":"Mandal","year":"2012","journal-title":"Singapore Med J"},{"key":"2025082708375610000_14.8.e243697.9","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jceh.2014.05.014","article-title":"Pregnancy with portal hypertension","volume":"4","author":"Aggarwal","year":"2014","journal-title":"J Clin Exp Hepatol"},{"key":"2025082708375610000_14.8.e243697.10","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/ajg.2015.430","article-title":"Acg clinical guideline: liver disease and pregnancy","volume":"111","author":"Tran","year":"2016","journal-title":"Am J Gastroenterol"},{"key":"2025082708375610000_14.8.e243697.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.06.004"},{"key":"2025082708375610000_14.8.e243697.12","doi-asserted-by":"crossref","unstructured":"Consensus on extra-hepatic portal vein obstruction. 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