{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:40:01Z","timestamp":1756294801752,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,7,13]]},"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:p>Raynaud\u2019s phenomenon (RP) is a well-known disorder of self-limiting paroxysmal vasospasms occurring in small arteries of the digits, in the order of skin pallor (white), followed by cyanosis (blue), ending with hyperemia (red). These designative triphasic colour changes with exposure to cold, or emotional response is diagnostic in adults. RP is a very rare phenomenon in the young paediatric population as noted by Nigrovic <jats:italic>et al<\/jats:italic> with 123 patients &lt;19\u2009year old in a large children\u2019s centre over 10 years and only 4 patients being &lt;2 years old, with 69% of these being primary RP. To our knowledge, this is the youngest documented case of Raynaud\u2019s disease that has not required treatment.<\/jats:p>","DOI":"10.1136\/bcr-2021-243848","type":"journal-article","created":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T11:30:18Z","timestamp":1627385418000},"page":"e243848","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["I am blue: a toddler\u2019s Raynaud\u2019s phenomenon"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3885-6069","authenticated-orcid":false,"given":"Yae Sul","family":"Jeong","sequence":"first","affiliation":[{"name":"Pediatric Emergency Medicine, Beaumont Health, Royal Oak, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Menoch","sequence":"additional","affiliation":[{"name":"Pediatric Emergency Medicine, Beaumont Health, Royal Oak, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,7,27]]},"reference":[{"key":"2025082703580603000_14.7.e243848.1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.111.4.715"},{"key":"2025082703580603000_14.7.e243848.2","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/s41401-018-0055-1","article-title":"Expression of the oxygen-sensitive transcription factor subunit HIF-1\u03b1 in patients suffering from secondary Raynaud syndrome","volume":"40","author":"Heger","year":"2019","journal-title":"Acta Pharmacol Sin"},{"key":"2025082703580603000_14.7.e243848.3","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/pde.13129","article-title":"Handy hints about Raynaud's phenomenon in children: a critical review","volume":"34","author":"Rigante","year":"2017","journal-title":"Pediatr Dermatol"},{"key":"2025082703580603000_14.7.e243848.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)05118-7"},{"key":"2025082703580603000_14.7.e243848.5","first-page":"313","article-title":"[Mycoplasma pneumoniae infection. Manifestation in a 3-year-old child by Raynaud's phenomenon]","volume":"42","author":"Furioli","year":"1985","journal-title":"Arch Fr Pediatr"},{"key":"2025082703580603000_14.7.e243848.6","doi-asserted-by":"publisher","DOI":"10.1099\/jmmcr.0.005117"},{"key":"2025082703580603000_14.7.e243848.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-857X(03)00019-X"},{"key":"2025082703580603000_14.7.e243848.8","first-page":"264","article-title":"Raynaud phenomenon in children","volume":"65","author":"Goldman","year":"2019","journal-title":"Can Fam Physician"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-243848","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:58:25Z","timestamp":1756292305000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-243848"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":8,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2021,7,27]]},"published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1136\/bcr-2021-243848"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-243848","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}