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The diagnosis of myasthenia gravis was based on suggestive symptoms of fatigable bilateral orbital ptosis, diplopia, positive ocular cold compression test and serum acetylcholine receptor antibody positivity, as well as a favourable treatment response to pyridostigmine. The addition of corticosteroids and methotrexate resulted in complete resolution of the ocular signs.<\/jats:p>","DOI":"10.1136\/bcr-2021-244102","type":"journal-article","created":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T13:00:51Z","timestamp":1628686851000},"page":"e244102","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":17,"title":["Transient acetylcholine receptor-related myasthenia gravis, post multisystem inflammatory syndrome in children (MIS-C) temporally associated with COVID-19 infection"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4590-544X","authenticated-orcid":false,"given":"Farida","family":"Essajee","sequence":"first","affiliation":[{"name":"Pediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juanita","family":"Lishman","sequence":"additional","affiliation":[{"name":"Pediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5607-8443","authenticated-orcid":false,"given":"Regan","family":"Solomons","sequence":"additional","affiliation":[{"name":"Pediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepthi Raju","family":"Abraham","sequence":"additional","affiliation":[{"name":"Pediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1146-1307","authenticated-orcid":false,"given":"Pierre","family":"Goussard","sequence":"additional","affiliation":[{"name":"Pediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald","family":"Van Toorn","sequence":"additional","affiliation":[{"name":"Pediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,8,11]]},"reference":[{"key":"2025082708234587000_14.8.e244102.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2020.102597"},{"key":"2025082708234587000_14.8.e244102.2","unstructured":".\u2019 Centers for Disease Control and Prevention (CDC), . 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