{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T08:06:18Z","timestamp":1785830778019,"version":"3.56.0"},"reference-count":21,"publisher":"BMJ","issue":"8","license":[{"start":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T00:00:00Z","timestamp":1629763200000},"content-version":"unspecified","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,8,8]]},"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:p>A rare cause of olfactory impairment is olfactory groove meningiomas with insidious onset of non-specific symptoms like headache, olfactory dysfunction, psychiatric symptoms such as depression, personality changes, declining cognitive function, visual disturbances or seizures. A common complication of surgery is loss of olfactory function. Still, the preservation of olfactory function should be attempted as olfactory loss often has a severe negative impact on quality of life. This report describes a woman with an olfactory groove meningioma and a 10-year history of olfactory impairment. It includes preoperatively and postoperatively extended olfactory testing, a neurosurgical approach to preserve the olfactory function and postoperative olfactory rehabilitation. After rehabilitation, the patient regained a normal olfactory function, even though the right-sided olfactory nerve could not be preserved during surgery. The case demonstrates the importance of performing neuroimaging in selected patients with olfactory loss and a method for preserving and potentially improving postoperative olfactory function.<\/jats:p>","DOI":"10.1136\/bcr-2021-244145","type":"journal-article","created":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T13:10:14Z","timestamp":1629897014000},"page":"e244145","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["Olfactory groove meningioma with a 10-year history of smell loss and olfactory recovery after surgery"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4535-127X","authenticated-orcid":false,"given":"Andreas Steenholt","family":"Niklassen","sequence":"first","affiliation":[{"name":"Flavour Institute, Department of Clinical Medicine, Aarhus Universitet, Aarhus C, Denmark"},{"name":"Department of Ear, nose and throat, Regional Hospital West, Holstebro, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasmus Langelund","family":"J\u00f8rgensen","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Aarhus University Hospital, Aarhus N, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9135-6920","authenticated-orcid":false,"given":"Alexander Wieck","family":"Fjaeldstad","sequence":"additional","affiliation":[{"name":"Flavour Institute, Department of Clinical Medicine, Aarhus Universitet, Aarhus C, Denmark"},{"name":"Department of Ear, nose and throat, Regional Hospital West, Holstebro, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,8,25]]},"reference":[{"key":"2025082708204112000_14.8.e244145.1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.clineuro.2018.05.016","article-title":"Surgical and functional outcome of olfactory groove meningiomas: lessons from the past experience and strategy development","volume":"171","author":"Fountas","year":"2018","journal-title":"Clin Neurol Neurosurg"},{"key":"2025082708204112000_14.8.e244145.2","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-010-0386-3"},{"key":"2025082708204112000_14.8.e244145.3","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1984.03340250033016"},{"key":"2025082708204112000_14.8.e244145.4","doi-asserted-by":"crossref","DOI":"10.1007\/s00701-006-1075-z","article-title":"Olfactory groove meningiomas: functional outcome in a series treated microsurgically","volume":"149","author":"Bassiouni","year":"2007","journal-title":"Acta Neurochir"},{"key":"2025082708204112000_14.8.e244145.5","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1016\/j.clineuro.2012.12.004","article-title":"Preservation of olfaction in surgery of olfactory groove meningiomas","volume":"115","author":"Jang","year":"2013","journal-title":"Clin Neurol Neurosurg"},{"key":"2025082708204112000_14.8.e244145.6","doi-asserted-by":"publisher","DOI":"10.1093\/chemse\/bjt072"},{"key":"2025082708204112000_14.8.e244145.7","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1002\/lary.27052","article-title":"Danish validation of Sniffin' sticks olfactory test for threshold, discrimination, and identification","volume":"128","author":"Niklassen","year":"2018","journal-title":"Laryngoscope"},{"key":"2025082708204112000_14.8.e244145.8","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200410000-00017"},{"key":"2025082708204112000_14.8.e244145.9","article-title":"Patients and experiences from the first Danish flavour clinic","volume":"67","author":"Fjaeldstad","year":"2020","journal-title":"Dan Med J"},{"key":"2025082708204112000_14.8.e244145.10","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1001\/jamaoto.2014.1883","article-title":"Routine magnetic resonance imaging for idiopathic olfactory loss: a modeling-based economic evaluation","volume":"140","author":"Rudmik","year":"2014","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"2025082708204112000_14.8.e244145.11","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24248"},{"key":"2025082708204112000_14.8.e244145.12","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/alr.21066","article-title":"Cost effectiveness of magnetic resonance imaging in the workup of the dysosmia patient","volume":"3","author":"Decker","year":"2013","journal-title":"Int Forum Allergy Rhinol"},{"key":"2025082708204112000_14.8.e244145.13","doi-asserted-by":"crossref","first-page":"685","DOI":"10.3109\/02688697.2015.1054348","article-title":"Resection of olfactory groove meningioma - a review of complications and prognostic factors","volume":"29","author":"Mukherjee","year":"2015","journal-title":"Br J Neurosurg"},{"key":"2025082708204112000_14.8.e244145.14","doi-asserted-by":"crossref","DOI":"10.1227\/01.NEU.0000255453.20602.80","article-title":"Olfactory groove meningiomas: clinical outcome and recurrence rates after tumor removal through the frontolateral and bifrontal approach","volume":"60","author":"Nakamura","year":"2007","journal-title":"Neurosurgery"},{"key":"2025082708204112000_14.8.e244145.15","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1007\/s00701-019-03821-8","article-title":"Preservation of olfaction in anterior midline skull base meningiomas: a comprehensive approach","volume":"161","author":"Ung","year":"2019","journal-title":"Acta Neurochir"},{"key":"2025082708204112000_14.8.e244145.16","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1055\/s-0033-1333618","article-title":"The role of the Pterional approach in the surgical treatment of olfactory groove meningiomas: a 20-year experience","volume":"74","author":"Bitter","year":"2013","journal-title":"J Neurol Surg B Skull Base"},{"key":"2025082708204112000_14.8.e244145.17","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.70.2.218"},{"key":"2025082708204112000_14.8.e244145.18","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.wneu.2016.06.101","article-title":"Olfactory groove meningiomas: comparison of extent of frontal lobe changes after lateral and Bifrontal approaches","volume":"94","author":"Nanda","year":"2016","journal-title":"World Neurosurg"},{"key":"2025082708204112000_14.8.e244145.19","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1007\/s00701-017-3303-0","article-title":"Limitations of the endonasal endoscopic approach in treating olfactory groove meningiomas. A systematic review","volume":"159","author":"Shetty","year":"2017","journal-title":"Acta Neurochir"},{"key":"2025082708204112000_14.8.e244145.20","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1007\/s10143-019-01193-2","article-title":"Endoscopic endonasal versus transcranial approach to resection of olfactory groove meningiomas: a systematic review","volume":"43","author":"Purohit","year":"2020","journal-title":"Neurosurg Rev"},{"key":"2025082708204112000_14.8.e244145.21","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1055\/s-2008-1058189","article-title":"Return of olfaction after gross total resection of an olfactory groove meningioma: case report","volume":"8","author":"Gerber","year":"1998","journal-title":"Skull Base Surg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-244145","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:20:50Z","timestamp":1756308050000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-244145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":21,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2021,8,25]]},"published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1136\/bcr-2021-244145"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-244145","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8]]}}}