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CBPB overall has a very poor prognosis with a 5-year survival rate of only 15%. Our patient presented with cough and haemoptysis. Her chest radiograph demonstrated a large right-sided lung mass. Further investigations included CT, CT-guided biopsy and PET CT which were discussed at multidisciplinary team meetings. The patient then underwent complete surgical excision. We report this rare malignancy with radiological and pathological features, comparing them with previously reported cases.<\/jats:p>","DOI":"10.1136\/bcr-2021-244151","type":"journal-article","created":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T13:22:36Z","timestamp":1628601756000},"page":"e244151","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Classic biphasic pulmonary blastoma (CBPB): a rare primary pulmonary malignancy"],"prefix":"10.1136","volume":"14","author":[{"given":"Shashank","family":"Pooniya","sequence":"first","affiliation":[{"name":"Clinical Radiology, Ninewells Hospital and Medical School, Dundee, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"McKinnie","sequence":"additional","affiliation":[{"name":"Clinical Radiology, Ninewells Hospital and Medical School, Dundee, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Taylor","sequence":"additional","affiliation":[{"name":"Clinical Radiology, Ninewells Hospital and Medical School, Dundee, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malcolm","family":"Will","sequence":"additional","affiliation":[{"name":"Consultant Cardiothoracic Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Wallace","sequence":"additional","affiliation":[{"name":"Professor Pathology, Royal Infirmary of Edinburgh, Edinburgh, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,8,10]]},"reference":[{"key":"2025082722193073000_14.8.e244151.1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19980201)82:3<462::AID-CNCR6>3.0.CO;2-R"},{"key":"2025082722193073000_14.8.e244151.2","first-page":"507","article-title":"What do we know about pulmonary blastoma?: review of literature and clinical case report","volume":"78","author":"Brodowska-Kania","year":"2016","journal-title":"Nagoya J Med Sci"},{"key":"2025082722193073000_14.8.e244151.3","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19910501)67:9<2368::AID-CNCR2820670926>3.0.CO;2-G"},{"key":"2025082722193073000_14.8.e244151.4","doi-asserted-by":"crossref","first-page":"030006052096239","DOI":"10.1177\/0300060520962394","article-title":"Classic biphasic pulmonary blastoma: a case report and review of the literature","volume":"48","author":"Luo","year":"2020","journal-title":"J Int Med Res"},{"key":"2025082722193073000_14.8.e244151.5","doi-asserted-by":"crossref","DOI":"10.1186\/s12885-020-07323-0","article-title":"Epidemiological features and survival outcomes in patients with malignant pulmonary blastoma: a US population-based analysis","volume":"20","author":"Bu","year":"2020","journal-title":"BMC Cancer"},{"key":"2025082722193073000_14.8.e244151.6","first-page":"983","article-title":"Classic biphasic pulmonary blastoma with brain and axillary metastases: a case report with molecular analysis and review of literature","volume":"8","author":"Xiu","year":"2015","journal-title":"Int J Clin Exp Pathol"},{"key":"2025082722193073000_14.8.e244151.7","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.18003212802"},{"key":"2025082722193073000_14.8.e244151.8","unstructured":"WHO Classification of Tumours Editorial Board . 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