{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T14:19:07Z","timestamp":1758637147164,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"3","funder":[{"DOI":"10.13039\/100009874","name":"Universit\u00e9 de Sherbrooke","doi-asserted-by":"publisher","award":["D\u00e9partement de chirurgie"],"award-info":[{"award-number":["D\u00e9partement de chirurgie"]}],"id":[{"id":"10.13039\/100009874","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,2,17]]},"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:p>Gastrosplenic fistula is a rare and potentially fatal clinical entity unknown to most healthcare providers. Its diagnosis and management are challenging; and addressing it too late can have devastating consequences for patients. To increase awareness about this pathology, we hereby present a case of asymptomatic gastrosplenic fistula arising from a diffuse large B cell lymphoma in a 60-year-old Caucasian man with no significant medical history. The patient was successfully treated with open <jats:italic>en-bloc<\/jats:italic> splenectomy and partial gastrectomy. The patient was discharged from the hospital 3\u2009days after the surgery. At 1-month postoperatively, the patient was asymptomatic and presented no complication of the surgery. He went on to finish six cycles of chemotherapy (R-EPOCH, rituximab, etoposide phosphate, prednisone, vincristine sulfate, cyclophosphamide, doxorubicin hydrochloride) and achieved complete metabolic response. At 2\u2009years after the surgery, the patient remains asymptomatic and presents no sign of disease recurrence.<\/jats:p>","DOI":"10.1136\/bcr-2021-244259","type":"journal-article","created":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T10:50:18Z","timestamp":1646650218000},"page":"e244259","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Successful multidisciplinary management of an asymptomatic gastrosplenic fistula in a diffuse large B cell lymphoma patient"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0034-8088","authenticated-orcid":false,"given":"Sarah","family":"Mansouri","sequence":"first","affiliation":[{"name":"General Surgery, University of Sherbrooke Faculty of Medicine and Health Sciences, Sherbrooke, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4180-1926","authenticated-orcid":false,"given":"Chadey","family":"Assane","sequence":"additional","affiliation":[{"name":"General Surgery, University of Sherbrooke Faculty of Medicine and Health Sciences, Sherbrooke, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4876-7185","authenticated-orcid":false,"given":"Francois-Charles","family":"Malo","sequence":"additional","affiliation":[{"name":"General Surgery, University of Sherbrooke Faculty of Medicine and Health Sciences, Sherbrooke, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,3,7]]},"reference":[{"key":"2025082711295140000_15.3.e244259.1","doi-asserted-by":"crossref","first-page":"6491","DOI":"10.3748\/wjg.v23.i35.6491","article-title":"Gastrosplenic fistula occurring in lymphoma patients: systematic review with a new case of extranodal NK\/T-cell lymphoma","volume":"23","author":"Kang","year":"2017","journal-title":"World J Gastroenterol"},{"key":"2025082711295140000_15.3.e244259.2","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ijscr.2016.02.017","article-title":"Massive gastrointestinal bleeding after chemotherapy for gastric lymphoma","volume":"21","author":"Sousa","year":"2016","journal-title":"Int J Surg Case Rep"},{"key":"2025082711295140000_15.3.e244259.3","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1007\/s00277-013-1986-8","article-title":"Asymptomatic gastrosplenic fistula in a patient with marginal zonal lymphoma transformed to diffuse large B cell lymphoma--a case report and review of literature","volume":"93","author":"Senapati","year":"2014","journal-title":"Ann Hematol"},{"key":"2025082711295140000_15.3.e244259.4","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V99.8.2685"},{"key":"2025082711295140000_15.3.e244259.5","first-page":"1898","article-title":"Gastrosplenic fistula in Hodgkin's lymphoma treated successfully by laparoscopic surgery and chemotherapy","volume":"28","author":"Al-Ashgar","year":"2007","journal-title":"Saudi Med J"},{"key":"2025082711295140000_15.3.e244259.6","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1159\/000500505","article-title":"Successful treatment of Gastrosplenic fistula arising from diffuse large B-cell lymphoma with chemotherapy: two case reports","volume":"12","author":"Saito","year":"2019","journal-title":"Case Rep Oncol"},{"key":"2025082711295140000_15.3.e244259.7","doi-asserted-by":"crossref","first-page":"153","DOI":"10.4143\/crt.2002.34.2.153","article-title":"Gastrosplenic Fistula Complicated in a Patient with Non- Hodgkin\u2019s Lymphoma","volume":"34","author":"Yang","year":"2002","journal-title":"Cancer Res Treat Off J Korean Cancer Assoc"},{"key":"2025082711295140000_15.3.e244259.8","doi-asserted-by":"crossref","DOI":"10.1136\/bcr.04.2010.2932","article-title":"Spontaneous gastrosplenic fistula secondary to primary splenic lymphoma","volume":"2010","author":"Khan","year":"2010","journal-title":"BMJ Case Rep"},{"key":"2025082711295140000_15.3.e244259.9","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.amsu.2018.03.025","article-title":"Management of gastrosplenic fistula in the emergency setting - 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