{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T13:59:37Z","timestamp":1780581577116,"version":"3.54.1"},"reference-count":25,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,10,2]]},"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:p>Substernal goitre is characterised by compressive symptoms of the airway and oesophagus. Chronic, progressive symptoms usually result in surgical removal. We report a rare presentation of substernal goitre in a male in his early 70s who suffered from severe bilateral lower extremity (LE) lymphoedema, resulting in immobility and nursing home placement, and left upper extremity lymphoedema. Our initial assessment led to a filariasis work-up, which was negative, due to the patient\u2019s prior 2-year residence in India and service overseas. Chest CT scan revealed an incidental substernal goitre extending posterior to the left innominate vein and aortic arch to the level of the left mainstem bronchus. The patient underwent a left hemithyroidectomy via cervical excision and sternotomy and had an uneventful recovery with resolution of lymphoedema and mobility. Despite extensive literature regarding clinical presentations of substernal goitre, severe lymphoedema of the LE is not a well-established association.<\/jats:p>","DOI":"10.1136\/bcr-2021-245036","type":"journal-article","created":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T13:10:18Z","timestamp":1635772218000},"page":"e245036","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Substernal goitre presenting with upper and lower extremity oedema"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5212-2187","authenticated-orcid":false,"given":"Rebekah LeAnn Bennett","family":"Daggett","sequence":"first","affiliation":[{"name":"School of Medicine, LSUHSC-S, Shreveport, Louisiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Farishta","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/HNS, LSUHSC-S, Shreveport, Louisiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Cuellar","sequence":"additional","affiliation":[{"name":"Department of Radiology, LSUHSC-S, Shreveport, Louisiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cherie-Ann O","family":"Nathan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/HNS, LSUHSC-S, Shreveport, Louisiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,11,1]]},"reference":[{"key":"2025082707161053000_14.11.e245036.1","doi-asserted-by":"publisher","DOI":"10.9738\/INTSURG-D-14-00041.1"},{"key":"2025082707161053000_14.11.e245036.2","doi-asserted-by":"crossref","first-page":"E65","DOI":"10.1055\/a-0918-3678","article-title":"Review of dancing parasites in lymphatic filariasis","volume":"5","author":"Dietrich","year":"2019","journal-title":"Ultrasound Int Open"},{"key":"2025082707161053000_14.11.e245036.3","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.ijscr.2017.01.003","article-title":"Patient-tailored management of an asymptomatic massive substernal goiter presenting as brachiocephalic vein occlusion. 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