{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T08:17:56Z","timestamp":1766391476465,"version":"3.44.0"},"reference-count":19,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,12,5]]},"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>Hereditary haemoglobinopathies are common disorders in Oman. The most common haematological disorder among Omani population is sickle cell disease (SCD). The spleen is one of the organs that is affected early in the first decade of life in SCD patients. Splenectomy has shown a high success rate in improving the quality of life in SCD patients, through eliminating acute splenic sequestration crises, thus reducing the need for hospital admission and transfusion requirements. One of the rare complications of splenectomy is porto-splenic vein thrombosis. Multiple factors are responsible for this complication including: thermal and mechanical injury during ligation of splenic hilum, sudden increase in the platelet count and large spleen size. We report a rare case of extensive porto-splenic vein thrombosis that responded to early initiation of anticoagulation with resolution of the thrombosis and recanalisation.<\/jats:p>","DOI":"10.1136\/bcr-2021-245085","type":"journal-article","created":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T10:47:37Z","timestamp":1642416457000},"page":"e245085","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Extensive porto-splenic venous thrombosis postsplenectomy in a sickle cell disease: a rare complication"],"prefix":"10.1136","volume":"15","author":[{"given":"Tamadher","family":"Al Barhi","sequence":"first","affiliation":[{"name":"General Surgery, Oman Medical Speciality Board, Al-Athaiba, Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4275-4524","authenticated-orcid":false,"given":"Yasser","family":"Wali","sequence":"additional","affiliation":[{"name":"Department of Child Health, Sultan Qaboos University, Muscat, Oman"},{"name":"Faculty of Medicine, Alexandria University, Alexandria, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sareyah","family":"Al Sibai","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sultan Qaboos University Hospital, Muscat, Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zainab","family":"Al Balushi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sultan Qaboos University Hospital, Muscat, Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,1,17]]},"reference":[{"key":"2025082713072824000_15.1.e245085.1","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s12687-013-0153-1","article-title":"Genetic services and testing in the sultanate of Oman. Sultanate of Oman steps into modern genetics","volume":"4","author":"Rajab","year":"2013","journal-title":"J Community Genet"},{"key":"2025082713072824000_15.1.e245085.2","doi-asserted-by":"crossref","first-page":"327","DOI":"10.5001\/omj.2019.64","article-title":"Hydroxyurea: pattern of use, patient adherence, and safety profile in patients with sickle cell disease in Oman","volume":"34","author":"Jose","year":"2019","journal-title":"Oman Med J"},{"key":"2025082713072824000_15.1.e245085.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcyt.2018.04.003"},{"key":"2025082713072824000_15.1.e245085.4","doi-asserted-by":"crossref","first-page":"316","DOI":"10.5144\/0256-4947.1997.316","article-title":"The role of splenectomy in patients with sickle cell disease","volume":"17","author":"Al-Salem","year":"1997","journal-title":"Ann Saudi Med"},{"key":"2025082713072824000_15.1.e245085.5","doi-asserted-by":"publisher","DOI":"10.1136\/adc.56.10.765"},{"key":"2025082713072824000_15.1.e245085.6","unstructured":"Al Salem A . Indications and complications of splenectomy for children with sickle cell disease, 2006. Available: https:\/\/www.jpedsurg.org\/article\/S0022-3468(06)00472-6\/fulltext [Accessed 08 Apr 2021]."},{"key":"2025082713072824000_15.1.e245085.7","doi-asserted-by":"publisher","DOI":"10.4103\/0971-5916.90984"},{"key":"2025082713072824000_15.1.e245085.8","doi-asserted-by":"crossref","first-page":"e482","DOI":"10.18295\/squmj.2016.16.04.013","article-title":"Laparoscopic splenectomy alone for sickle cell disease: account of 50 paediatric cases","volume":"16","author":"Al-Balushi","year":"2016","journal-title":"Sultan Qaboos Univ Med J"},{"key":"2025082713072824000_15.1.e245085.9","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.12682"},{"key":"2025082713072824000_15.1.e245085.10","first-page":"335","article-title":"Portal vein thrombosis after laparoscopic splenectomy: an ongoing clinical challenge","volume":"9","author":"Miniati","year":"2005","journal-title":"JSLS"},{"key":"2025082713072824000_15.1.e245085.11","first-page":"S22","article-title":"Preoperative transfusion versus no transfusion policy in sickle cell disease patients: a randomized trial","volume":"60 Suppl 1","author":"Elshinawy","year":"2020","journal-title":"Transfusion"},{"key":"2025082713072824000_15.1.e245085.12","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ijsu.2015.02.005","article-title":"Effects of surgical procedures on the occurrence and development of postoperative portal vein thrombosis in patients with cirrhosis complicated by portal hypertension","volume":"16","author":"Sun","year":"2015","journal-title":"Int J Surg"},{"key":"2025082713072824000_15.1.e245085.13","doi-asserted-by":"crossref","unstructured":"Portal or splenic vein thrombosis after splenectomy for immune cytopenia: a retrospective cohort study, 2015. Available: https:\/\/ashpublications.org\/blood\/article\/126\/23\/3483\/90804\/Portal-or-Splenic-Vein-Thrombosis-after [Accessed 17 May 2021].","DOI":"10.1182\/blood.V126.23.3483.3483"},{"key":"2025082713072824000_15.1.e245085.14","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.12682"},{"key":"2025082713072824000_15.1.e245085.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2006.06.036"},{"key":"2025082713072824000_15.1.e245085.16","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1993.01420170101015"},{"key":"2025082713072824000_15.1.e245085.17","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2000.16597"},{"key":"2025082713072824000_15.1.e245085.18","unstructured":"Turnes J . Portal hypertension\u2013related complications after acute portal vein thrombosis: impact of early anticoagulation, 2008. Available: https:\/\/www.cghjournal.org\/article\/S1542-3565(08)00798-2\/fulltext [Accessed 11 Apr 2021]."},{"key":"2025082713072824000_15.1.e245085.19","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2000.16597"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-245085","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T20:07:35Z","timestamp":1756325255000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-245085"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1,17]]},"published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1136\/bcr-2021-245085"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-245085","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2022,1]]}}}