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This case outlines the presentation and an unusual method of management of a patient diagnosed with a live tubal ectopic pregnancy with extensive medical and surgical history.<\/jats:p>","DOI":"10.1136\/bcr-2021-245149","type":"journal-article","created":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T10:50:11Z","timestamp":1646045411000},"page":"e245149","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Live tubal ectopic pregnancy managed with localised injection of methotrexate into gestational sac"],"prefix":"10.1136","volume":"15","author":[{"given":"Charlotte","family":"Wildblood","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Royal London Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Royal London Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joe","family":"Aquilina","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Royal London Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Gbegbaje","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Royal London Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,2,28]]},"reference":[{"key":"2025082700525358000_15.2.e245149.1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.14189"},{"key":"2025082700525358000_15.2.e245149.2","first-page":"329","article-title":"Use of methotrexate in the treatment of ectopic pregnancies: a retrospective single center study","volume":"11","author":"Beguin","year":"2020","journal-title":"Facts Views Vis Obgyn"},{"key":"2025082700525358000_15.2.e245149.3","doi-asserted-by":"crossref","first-page":"338.e1","DOI":"10.1016\/j.ajog.2008.12.006","article-title":"Yolk sac on transvaginal ultrasound as a prognostic indicator in the treatment of ectopic pregnancy with single-dose methotrexate","volume":"200","author":"Lipscomb","year":"2009","journal-title":"Am J Obstet Gynecol"},{"key":"2025082700525358000_15.2.e245149.4","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S0015-0282(16)57290-2","article-title":"Limited role for intratubal methotrexate treatment of ectopic pregnancy","volume":"63","author":"Shalev","year":"1995","journal-title":"Fertil Steril"},{"key":"2025082700525358000_15.2.e245149.5","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.jmig.2014.01.009","article-title":"Nonsurgical management of live tubal ectopic pregnancy by ultrasound-guided local injection and systemic methotrexate","volume":"21","author":"Wang","year":"2014","journal-title":"J Minim Invasive Gynecol"},{"key":"2025082700525358000_15.2.e245149.6","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1999.13020131.x"},{"key":"2025082700525358000_15.2.e245149.7","doi-asserted-by":"crossref","DOI":"10.1093\/hropen\/hoaa025","article-title":"Exclusive use of intrasac potassium chloride and methotrexate for treating cesarean scar pregnancy: effectiveness and subsequent fecundity","volume":"2020","author":"Gundewar","year":"2020","journal-title":"Hum Reprod Open"},{"key":"2025082700525358000_15.2.e245149.8","unstructured":"Methotrexate . Secondary methotrexate June 3, 2020, 2020. 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