{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:10:06Z","timestamp":1756311006236,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,3,11]]},"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p>A woman in her 40s presented with a 3-month history of intermittent bilateral daily headache of moderate intensity. She had severe headaches for almost 1\u2009month prior to the presentation, which was aggravated by standing and relieved by lying down. She underwent a non-contrast CT of the head followed by MRI of the brain and spine. Neuroimaging of the brain showed features of intracranial hypotension and spine MRI myelography fast imaging employing steady state acquisition sequences confirmed the site of cerebrospinal fluid (CSF) leak. An epidural blood patch (EBP) was placed to close the CSF leakage site. She had significant improvement in her symptoms and repeat MRI at 4\u2009weeks of follow-up showed resolution of imaging abnormalities. She became symptom-free without the requirement of additional EBP. Our report highlights the importance of suspecting and evaluating spontaneous intracranial hypotension in a patient presented with a typical orthostatic headache. Early intervention and keeping a low threshold for evaluation based on a few early clinical and imaging clues can lead to successful management of such cases.<\/jats:p>","DOI":"10.1136\/bcr-2021-245222","type":"journal-article","created":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T12:54:11Z","timestamp":1653310451000},"page":"e245222","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Case of spontaneous intracranial hypotension: clinical, neuroimaging and treatment approach"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1415-8522","authenticated-orcid":false,"given":"Govinda","family":"Siripurapu","sequence":"first","affiliation":[{"name":"Neurology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Awadh Kishor","family":"Pandit","sequence":"additional","affiliation":[{"name":"Neurology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0641-7398","authenticated-orcid":false,"given":"Divya M","family":"Radhakrishnan","sequence":"additional","affiliation":[{"name":"Neurology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4590-7947","authenticated-orcid":false,"given":"Achal Kumar","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Neurology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,5,10]]},"reference":[{"key":"2025082708301239000_15.5.e245222.1","doi-asserted-by":"crossref","DOI":"10.1001\/jamaneurol.2020.4799","article-title":"Clinical presentation, investigation findings, and treatment outcomes of spontaneous intracranial hypotension syndrome: a systematic review and meta-analysis","volume":"78","author":"D'Antona","year":"2021","journal-title":"JAMA Neurol"},{"key":"2025082708301239000_15.5.e245222.2","doi-asserted-by":"crossref","unstructured":"Podkovik S , Kashyap S , Bonda S , et al . 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