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Spontaneous heparin-induced thrombocytopaenia was diagnosed by heparin-induced platelet activation test with light transmission aggregometry. The patient was successfully treated with fondaparinux and intravenous immunoglobulin. Apixaban was given after recovery of platelet count. Resolution of both thrombus along aorta and adrenal haemorrhage were shown by CT of whole abdomen after 2 months of treatment. Our case demonstrates that this serious complication is important but seldom recognised early.<\/jats:p>","DOI":"10.1136\/bcr-2021-245385","type":"journal-article","created":{"date-parts":[[2021,11,29]],"date-time":"2021-11-29T09:40:35Z","timestamp":1638178835000},"page":"e245385","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Spontaneous heparin-induced thrombocytopaenia with adrenal haemorrhage following orthopaedic surgery: a case report and literature review"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4473-9216","authenticated-orcid":false,"given":"Supawee","family":"Saengboon","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Thammasat University, Pathum Thani, 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