{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T06:48:46Z","timestamp":1783061326903,"version":"3.54.6"},"reference-count":9,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,10,7]]},"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:p>Renal cell carcinoma (RCC) frequently presents with osseous metastasis, predominantly lytic and prone to pathological fracture. The metastatic lesion in the extremity presents with local swelling, pain and immobility due to pathological fracture. The solitary or oligometastatic lesions should be treated with curative intent, which can help the patient to lead a more prolonged and disability-free life. The RCCs and their metastases are hypervascular with an exuberant arterial supply. Surgery can lead to uncontrolled life-threatening haemorrhage. Preoperative transarterial embolisation reduces tumour vascularity significantly and reduces intraoperative blood loss. We present a 46-year-old male patient with solitary hypervascular metastatic recurrence of RCC with a pathological femoral fracture with an infeasible initial surgery due to profuse haemorrhage. He was successfully treated by preoperative transarterial embolisation, followed by surgical resection and implantation of a megaprosthesis. Multidisciplinary management reduces patient morbidity and mortality with successful treatment in solitary hypervascular metastasis from RCC.<\/jats:p>","DOI":"10.1136\/bcr-2021-245422","type":"journal-article","created":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T11:26:39Z","timestamp":1636457199000},"page":"e245422","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Multidisciplinary management of solitary hypervascular metastatic recurrence of renal cell carcinoma presenting with pathological femoral fracture"],"prefix":"10.1136","volume":"14","author":[{"given":"Sudipta","family":"Mohakud","sequence":"first","affiliation":[{"name":"Radiodiagnosis, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0179-9910","authenticated-orcid":false,"given":"Sujit","family":"Tripathy","sequence":"additional","affiliation":[{"name":"Orthopaedics, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nerbadyswari Deep","family":"Bag","sequence":"additional","affiliation":[{"name":"Radiodiagnosis, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitasha","family":"Mishra","sequence":"additional","affiliation":[{"name":"Anaesthesia, All India Institute of Medical Sciences - Bhubaneswar, Bhubaneswar, Orissa, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,11,9]]},"reference":[{"key":"2025082800443822000_14.11.e245422.1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-014-3734-3"},{"key":"2025082800443822000_14.11.e245422.2","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1038\/s41585-018-0034-9","article-title":"An interdisciplinary consensus on the management of bone metastases from renal cell carcinoma","volume":"15","author":"Gr\u00fcnwald","year":"2018","journal-title":"Nat Rev Urol"},{"key":"2025082800443822000_14.11.e245422.3","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0083026"},{"key":"2025082800443822000_14.11.e245422.4","doi-asserted-by":"crossref","DOI":"10.3390\/ijms17060987","article-title":"Bone metastasis from renal cell carcinoma","volume":"17","author":"Chen","year":"2016","journal-title":"Int J Mol Sci"},{"key":"2025082800443822000_14.11.e245422.5","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1080\/02841860701280725","article-title":"Selective palliative transcatheter embolization of bony metastases from renal cell carcinoma","volume":"46","author":"Forauer","year":"2007","journal-title":"Acta Oncol"},{"key":"2025082800443822000_14.11.e245422.6","doi-asserted-by":"crossref","first-page":"491","DOI":"10.3109\/17453678408992944","article-title":"Surgical removal of bone and muscle metastases of renal cancer","volume":"55","author":"Stener","year":"1984","journal-title":"Acta Orthop Scand"},{"key":"2025082800443822000_14.11.e245422.7","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.4037"},{"key":"2025082800443822000_14.11.e245422.8","doi-asserted-by":"publisher","DOI":"10.1016\/s1051-0443(96)70738-8"},{"key":"2025082800443822000_14.11.e245422.9","doi-asserted-by":"publisher","DOI":"10.1016\/S1051-0443(98)70267-2"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-245422","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:44:48Z","timestamp":1756367088000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-245422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":9,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2021,11,9]]},"published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1136\/bcr-2021-245422"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-245422","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11]]}}}