{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:05:25Z","timestamp":1756339525266,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,9,25]]},"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:p>Primary phlebitis of the central nervous system (PPCNS) is a rare condition that might be a subset of primary angiitis of the CNS. In this case report, the patient was a 39-year-old man with a 2-week history of anterograde amnesia and abnormal behaviours. Black-blood MRI (BB-MRI) showed contrast enhancement of the left basilar vein and cerebral superficial veins. Angiography showed unremarkable change in arteries. After a thorough differential diagnosis, we diagnosed PPCNS and then administered methylprednisolone pulse and cyclophosphamide pulse. The neuropsychological symptoms and MRI findings gradually improved, and after 2 months, the dose of prednisolone was gradually reduced to 20 mg. No recurrence was observed. This case shows that BB-MRI may be useful for diagnosing PPCNS.<\/jats:p>","DOI":"10.1136\/bcr-2021-245682","type":"journal-article","created":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T13:43:37Z","timestamp":1634132617000},"page":"e245682","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Primary phlebitis of central nervous system revealed by black-blood magnetic resonance imaging"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9502-1554","authenticated-orcid":false,"given":"Jinsoo","family":"Koh","sequence":"first","affiliation":[{"name":"Department of Neurology, Wakayama Medical University, Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junko","family":"Taruya","sequence":"additional","affiliation":[{"name":"Department of Neurology, Wakayama Medical University, Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megumi","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Neurology, Wakayama Medical University, Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidefumi","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Neurology, Wakayama Medical University, Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,10,13]]},"reference":[{"key":"2025082709171394000_14.10.e245682.1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000738"},{"key":"2025082709171394000_14.10.e245682.2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(11)70081-3"},{"key":"2025082709171394000_14.10.e245682.3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2012.00743.x"},{"key":"2025082709171394000_14.10.e245682.4","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.116.016194"},{"key":"2025082709171394000_14.10.e245682.5","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20160496"},{"key":"2025082709171394000_14.10.e245682.6","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/neup.12234","article-title":"Central nervous system granulomastous phlebitis with limited extracranial involvement of the heart and lungs: an autopsy case","volume":"36","author":"Mlakar","year":"2016","journal-title":"Neuropathology"},{"key":"2025082709171394000_14.10.e245682.7","doi-asserted-by":"crossref","DOI":"10.1093\/rheumatology\/kez058.037","article-title":"097.\u2003Primary central nervous system (CNS) phlebitis","volume":"58","author":"Keat","year":"2019","journal-title":"Rheumatology"},{"key":"2025082709171394000_14.10.e245682.8","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2009.76"},{"key":"2025082709171394000_14.10.e245682.9","doi-asserted-by":"crossref","DOI":"10.1177\/1756286418785071","article-title":"Primary angiitis of the central nervous system: diagnosis and treatment","volume":"11","author":"Beuker","year":"2018","journal-title":"Ther Adv Neurol Disord"},{"key":"2025082709171394000_14.10.e245682.10","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60069-5"},{"key":"2025082709171394000_14.10.e245682.11","doi-asserted-by":"publisher","DOI":"10.1136\/practneurol-2018-002002"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-245682","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:17:22Z","timestamp":1756311442000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-245682"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":11,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2021,10,13]]},"published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1136\/bcr-2021-245682"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-245682","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2021,10]]}}}