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CT of the thorax, abdomen and pelvis showed mild hepatosplenomegaly with small pathological lymph nodes throughout the abdomen. Bone marrow biopsy was unremarkable. Lymph node biopsy was difficult to achieve, and therefore a positron emission tomography scan was arranged. This showed an enlarged and hypermetabolic spleen. Differential diagnoses at this point included lymphoma and sarcoidosis. He underwent diagnostic splenectomy, and the diagnosis of sarcoidosis was confirmed histologically. Calcium level remained normal 17 months after splenectomy.<\/jats:p>","DOI":"10.1136\/bcr-2021-245987","type":"journal-article","created":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T14:17:59Z","timestamp":1634134679000},"page":"e245987","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Isolated splenic sarcoidosis: a rare cause of hypercalcaemia in a patient with type 1 diabetes"],"prefix":"10.1136","volume":"14","author":[{"given":"Hafiz Muhammad","family":"Zubair Ullah","sequence":"first","affiliation":[{"name":"Deaprtment of Diabetes and Endocrinology, University Hospital of Wales, Cardiff, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashutosh","family":"Surya","sequence":"additional","affiliation":[{"name":"Deaprtment of Diabetes and Endocrinology, University Hospital of Wales, Cardiff, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Morley","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Velindre Cancer Centre, Cardiff, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sajjad","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Deaprtment of Diabetes and Endocrinology, University Hospital of Wales, Cardiff, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,10,13]]},"reference":[{"key":"2025082800544232000_14.10.e245987.1","first-page":"42","article-title":"Anomalous disease of the skin of the fingers: case of livid papillary psoriasis","volume":"1","author":"Hutchinson","year":"1877","journal-title":"Illus. 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