{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T04:51:47Z","timestamp":1773377507306,"version":"3.50.1"},"reference-count":18,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,10,11]]},"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:p>M\u00e9n\u00e9trier\u2019s disease (MD) is a rare disease of the stomach, characterised by hypertrophic gastric folds leading to protein loss. The association with ulcerative colitis (UC) is rare but has been reported in the literature. We report a case of a 29-year-old male affected by UC with an additional diagnosis of MD 3 years after UC diagnosis. UC was refractory to several treatment lines (thiopurines, infliximab, vedolizumab and ustekinumab), and the patient underwent colectomy. Octreotide was administered for MD normalising blood biochemistry, but it was not effective in inducing endoscopic remission of the stomach. Treatment options in patients with MD and UC are discussed.<\/jats:p>","DOI":"10.1136\/bcr-2021-246137","type":"journal-article","created":{"date-parts":[[2021,10,19]],"date-time":"2021-10-19T17:01:07Z","timestamp":1634662867000},"page":"e246137","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["M\u00e9n\u00e9trier\u2019s disease in a patient with refractory ulcerative colitis: a clinical challenge and review of the literature"],"prefix":"10.1136","volume":"14","author":[{"given":"Sofia","family":"Rao","sequence":"first","affiliation":[{"name":"IBD-unit, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy"},{"name":"Section of Gastroenterology and Hepatology, PROMISE, University of Palermo, Palermo, Sicilia (omit), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Viola","sequence":"additional","affiliation":[{"name":"IBD-unit, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Ksissa","sequence":"additional","affiliation":[{"name":"IBD-unit, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy"},{"name":"Section of Gastroenterology and Hepatology, PROMISE, University of Palermo, Palermo, Sicilia (omit), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6159-7478","authenticated-orcid":false,"given":"Walter","family":"Fries","sequence":"additional","affiliation":[{"name":"IBD-unit, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,10,19]]},"reference":[{"key":"2025082708194154000_14.10.e246137.1","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.cgh.2020.03.017","article-title":"Survival times of patients with Menetrier's disease and risk of gastric cancer","volume":"19","author":"Almazar","year":"2021","journal-title":"Clin Gastroenterol Hepatol"},{"key":"2025082708194154000_14.10.e246137.2","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/BF02954726","article-title":"Menetrier's disease in a patient with ileocolonic Crohn's disease","volume":"152","author":"Arthurs","year":"1983","journal-title":"Ir J Med Sci"},{"key":"2025082708194154000_14.10.e246137.3","first-page":"96","article-title":"[A case report of Menetrier's disease developed in a patient with ulcerative colitis]","volume":"88","author":"Sasaki","year":"1991","journal-title":"Nihon Shokakibyo Gakkai Zasshi"},{"key":"2025082708194154000_14.10.e246137.4","first-page":"175","article-title":"[Menetrier disease associated with ulcerative colitis. 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