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Autoimmune dysfunction is frequent in the postpartum period and is closely related to PP. We report a case of a primiparous woman in her 20s with PP who did not respond to initial treatment with antipsychotics. After reassessment, SREAT was considered in the differential diagnosis. Neuropsychiatric symptoms improved dramatically after 72\u2009hours of treatment with high-dose steroids treatment and the patient was discharged after 16 days. In women with PP, an autoimmune cause must be ruled out before assuming a psychiatry aetiology.<\/jats:p>","DOI":"10.1136\/bcr-2021-246199","type":"journal-article","created":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T12:01:02Z","timestamp":1647259262000},"page":"e246199","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Steroid-responsive encephalopathy associated with autoimmune thyroiditis presenting with a postpartum psychosis"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6467-3875","authenticated-orcid":false,"given":"T\u00e2nia","family":"Silva","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University of Coimbra, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Psychiatry, Centro Hospitalar e Universit\u00e1rio de Coimbra EPE, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Esteves","sequence":"additional","affiliation":[{"name":"Psychiatry, Centro Hospitalar e Universit\u00e1rio de Coimbra EPE, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquim","family":"Cerejeira","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Coimbra, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,3,14]]},"reference":[{"key":"2025082800314508000_15.3.e246199.1","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/j.autrev.2016.09.008","article-title":"Steroid-Responsive encephalopathy associated with autoimmune thyroiditis (SREAT): characteristics, treatment and outcome in 251 cases from the literature","volume":"15","author":"Laurent","year":"2016","journal-title":"Autoimmun Rev"},{"key":"2025082800314508000_15.3.e246199.2","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.autrev.2016.01.014","article-title":"Hashimoto's encephalopathy: a rare proteiform disorder","volume":"15","author":"Montagna","year":"2016","journal-title":"Autoimmun Rev"},{"key":"2025082800314508000_15.3.e246199.3","doi-asserted-by":"crossref","first-page":"585","DOI":"10.5334\/tohm.420","article-title":"Steroid-Responsive encephalopathy associated with autoimmune thyroiditis (SREAT) presenting with pure cerebellar ataxia","volume":"8","author":"Termsarasab","year":"2018","journal-title":"Tremor Other Hyperkinet Mov"},{"key":"2025082800314508000_15.3.e246199.4","doi-asserted-by":"crossref","first-page":"23S","DOI":"10.1212\/WNL.48.Suppl_5.23S","article-title":"Serologic profile of myasthenia gravis and distinction from the Lambert-Eaton myasthenic syndrome","volume":"48","author":"Lennon","year":"1997","journal-title":"Neurology"},{"key":"2025082800314508000_15.3.e246199.5","doi-asserted-by":"crossref","first-page":"101321","DOI":"10.1016\/j.beem.2019.101321","article-title":"Exacerbations of autoimmune diseases during pregnancy and postpartum","volume":"33","author":"Borba","year":"2019","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"2025082800314508000_15.3.e246199.6","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s00737-016-0675-8","article-title":"Suicide and filicide in postpartum psychosis","volume":"20","author":"Brockington","year":"2017","journal-title":"Arch Womens Ment Health"},{"key":"2025082800314508000_15.3.e246199.7","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-010761"},{"key":"2025082800314508000_15.3.e246199.8","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s00737-009-0117-y","article-title":"Puerperal psychosis","volume":"13","author":"Boyce","year":"2010","journal-title":"Arch Womens Ment Health"},{"key":"2025082800314508000_15.3.e246199.9","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association . 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