{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T11:44:05Z","timestamp":1774611845865,"version":"3.50.1"},"reference-count":19,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/bmj.com\/coronavirus\/usage"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,11,14]]},"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:p>COVID-19 predominantly affects the respiratory system. As a novel disease, understanding of its management and complications continues to grow. Herein, we present a case of almost complete splenic infarction in a patient with COVID-19 pneumonia. This case highlights the need to maintain diagnostic vigilance whilst investigating secondary complications of COVID-19. It is also important to stress the high incidence of thromboembolic complications in patients with COVID-19, which may occur anywhere in the vasculature.<\/jats:p>","DOI":"10.1136\/bcr-2021-246274","type":"journal-article","created":{"date-parts":[[2021,12,7]],"date-time":"2021-12-07T11:24:06Z","timestamp":1638876246000},"page":"e246274","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Complete splenic infarction in association with COVID-19"],"prefix":"10.1136","volume":"14","author":[{"given":"Graham","family":"Prentice","sequence":"first","affiliation":[{"name":"Respiratory Department, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Wilson","sequence":"additional","affiliation":[{"name":"Respiratory Department, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Coupland","sequence":"additional","affiliation":[{"name":"Radiology Department, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Bicknell","sequence":"additional","affiliation":[{"name":"Respiratory Department, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,12,7]]},"reference":[{"key":"2025082707003584000_14.12.e246274.1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0234765"},{"key":"2025082707003584000_14.12.e246274.2","doi-asserted-by":"crossref","first-page":"100639","DOI":"10.1016\/j.eclinm.2020.100639","article-title":"Thromboembolism risk of COVID-19 is high and associated with a higher risk of mortality: a systematic review and meta-analysis","volume":"29","author":"Malas","year":"2020","journal-title":"EClinicalMedicine"},{"key":"2025082707003584000_14.12.e246274.3","unstructured":"et al Bagot C , Miles B , Chalmers G . Prevention of thrombosis in COVID-19 +ve adult inpatients (pregnant and non-pregnant) undergoing renal replacement therapy (RRT) on critical care wards. NHS greater Glasgow and Clyde Staffnet. Available: http:\/\/www.staffnet.ggc.scot.nhs.uk\/Acute\/Surgery%20Anaesthetics\/Critical%20Care\/QEUH_CCU\/Documents\/Thrombosis%20prevention%20for%20RRT%20patients%20in%20critical%20care%20Covid-19%20GGC%2016.04.20.pdf [Accessed 17 Feb 2021]."},{"key":"2025082707003584000_14.12.e246274.4","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1007\/s11739-020-02432-x","article-title":"COVID-19, coagulopathy and venous thromboembolism: more questions than answers","volume":"15","author":"Marietta","year":"2020","journal-title":"Intern Emerg Med"},{"key":"2025082707003584000_14.12.e246274.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2020.06.029"},{"key":"2025082707003584000_14.12.e246274.6","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1016\/S0140-6736(21)00676-0","article-title":"Tocilizumab in patients admitted to hospital with COVID-19 (recovery): a randomised, controlled, open-label, platform trial","volume":"397","author":"Horby","year":"2021","journal-title":"Lancet"},{"key":"2025082707003584000_14.12.e246274.7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2015432"},{"key":"2025082707003584000_14.12.e246274.8","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2015-212428"},{"key":"2025082707003584000_14.12.e246274.9","first-page":"1","article-title":"Splenic infarction in acute cytomegalovirus and human parvovirus concomitant infection","volume":"2018","author":"Harada","year":"2018","journal-title":"Case Rep Infect Dis"},{"key":"2025082707003584000_14.12.e246274.10","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.idcr.2016.04.003","article-title":"Splenic infarcts as a rare manifestation of parvovirus B19 infection","volume":"4","author":"Kranidiotis","year":"2016","journal-title":"IDCases"},{"key":"2025082707003584000_14.12.e246274.11","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.jvscit.2020.06.012","article-title":"Arterial thrombotic complications in COVID-19 patients","volume":"6","author":"Levolger","year":"2020","journal-title":"J Vasc Surg Cases and Innovative Techniques"},{"key":"2025082707003584000_14.12.e246274.12","doi-asserted-by":"publisher","DOI":"10.12890\/2020_001747"},{"key":"2025082707003584000_14.12.e246274.13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15761\/VDT.1000142","article-title":"Splenic infarct presenting as acute chest pain","volume":"2","author":"Pak","year":"2017","journal-title":"Vascul Dis Ther"},{"key":"2025082707003584000_14.12.e246274.14","first-page":"96","article-title":"A rare cause of acute abdominal pain: splenic infarct (case series)","volume":"15","author":"Ozakin","year":"2015","journal-title":"Turk J Emerg Med"},{"key":"2025082707003584000_14.12.e246274.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2008.02.014"},{"key":"2025082707003584000_14.12.e246274.16","first-page":"611","article-title":"Concomitant renal and splenic infarction as a complication of COVID-19: a case report and literature review","volume":"28","author":"Ramanathan","year":"2020","journal-title":"Infez Med"},{"key":"2025082707003584000_14.12.e246274.17","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8880143"},{"key":"2025082707003584000_14.12.e246274.18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2011.08843.x"},{"key":"2025082707003584000_14.12.e246274.19","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1080\/21645515.2017.1264797","article-title":"Recommended vaccinations for asplenic and hyposplenic adult patients","volume":"13","author":"Bonanni","year":"2017","journal-title":"Hum Vaccin Immunother"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-246274","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:01:15Z","timestamp":1756303275000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-246274"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":19,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2021,12,7]]},"published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1136\/bcr-2021-246274"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-246274","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12]]}}}