{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:05:32Z","timestamp":1756339532207,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,1,7]]},"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:p>An 89-year-old man with multiple episodes of inferior corneal oedema and low-grade anterior segment inflammation over 18 months was diagnosed and managed as viral keratitis; however, the episodes kept recurring every time treatment, vis-\u00e0-vis topical steroids, were tapered or stopped. History of cataract surgery few months prior to onset of the symptoms, lack of other features of viral keratitis, such as keratic precipitates and inferior corneal oedema in the presence of slight pupillary peaking led to the suspicion of either a retained lens fragment (RLF) or other possible iatrogenic insult. This was confirmed by anterior segment optical coherence tomogram, which revealed the RLF in inferior angle; this was removed surgically as an emergency procedure. This resulted in significant improvement in the corneal oedema, as well as marked symptomatic relief confirmed by the patient.<\/jats:p>","DOI":"10.1136\/bcr-2021-246334","type":"journal-article","created":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T13:32:06Z","timestamp":1649856726000},"page":"e246334","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Curious case of chronic corneal oedema"],"prefix":"10.1136","volume":"15","author":[{"given":"Ritika","family":"Mukhija","sequence":"first","affiliation":[{"name":"Sussex Eye Hospital, University Hospitals Sussex NHS Foundation Trust, Brighton, Sussex, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam","family":"Kanavati","sequence":"additional","affiliation":[{"name":"Sussex Eye Hospital, University Hospitals Sussex NHS Foundation Trust, Brighton, Sussex, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0667-3700","authenticated-orcid":false,"given":"Mayank A","family":"Nanavaty","sequence":"additional","affiliation":[{"name":"Sussex Eye Hospital, University Hospitals Sussex NHS Foundation Trust, Brighton, Sussex, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,4,13]]},"reference":[{"key":"2025082709531246000_15.4.e246334.1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31814b8bae"},{"key":"2025082709531246000_15.4.e246334.2","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1111\/ceo.12047","article-title":"Misdiagnosis of orthokeratology-related Acanthamoeba keratitis as herpes simplex virus keratitis","volume":"41","author":"Greenwell","year":"2013","journal-title":"Clin Exp Ophthalmol"},{"key":"2025082709531246000_15.4.e246334.3","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1055\/s-0031-1273344","article-title":"[Masquerade keratitis due to hereditary corneal disorders]","volume":"228","author":"Lisch","year":"2011","journal-title":"Klin Monbl Augenheilkd"},{"key":"2025082709531246000_15.4.e246334.4","doi-asserted-by":"crossref","first-page":"60","DOI":"10.3341\/kjo.2011.25.1.60","article-title":"A retained lens fragment induced anterior uveitis and corneal edema 15 years after cataract surgery","volume":"25","author":"Kang","year":"2011","journal-title":"Korean J Ophthalmol"},{"key":"2025082709531246000_15.4.e246334.5","article-title":"Five-Year-Old sequestered retained lens fragment requiring keratoplasty","volume":"12","author":"Giles","year":"2020","journal-title":"Cureus"},{"key":"2025082709531246000_15.4.e246334.6","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.jcrs.2010.11.022","article-title":"Retained nuclear fragment found during Descemet-stripping automated endothelial keratoplasty","volume":"37","author":"Mifflin","year":"2011","journal-title":"J Cataract Refract Surg"},{"key":"2025082709531246000_15.4.e246334.7","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/j.ajo.2015.08.019","article-title":"Clinical features and outcomes of retained lens fragments in the anterior chamber after phacoemulsification","volume":"160","author":"Zavodni","year":"2015","journal-title":"Am J Ophthalmol"},{"key":"2025082709531246000_15.4.e246334.8","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1016\/j.ophtha.2006.03.066","article-title":"Retained nuclear fragments in the anterior chamber after phacoemulsification with an intact posterior capsule","volume":"113","author":"Hui","year":"2006","journal-title":"Ophthalmology"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-246334","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:53:19Z","timestamp":1756313599000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-246334"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":8,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,4,13]]},"published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1136\/bcr-2021-246334"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-246334","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2022,4]]}}}