{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:13:01Z","timestamp":1756462381870,"version":"3.44.0"},"reference-count":25,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,11,11]]},"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:p>Primary amyloidosis is a rare systemic disorder often associated with multiple organ dysfunction. The most common form, light chain amyloidosis, has an estimated age-adjusted incidence of 5.1\u201312.8 cases per million person-years. Spine involvement is extremely uncommon. We present the case of a young Asian man with newly diagnosed amyloidosis involving the lumbar spine among multiple organs with a pathological vertebral fracture that required urgent spine surgery. We believe this is the first reported case to discuss the perianaesthetic challenges in the management of lumbar spine amyloidosis.<\/jats:p>","DOI":"10.1136\/bcr-2021-246359","type":"journal-article","created":{"date-parts":[[2021,11,29]],"date-time":"2021-11-29T09:40:41Z","timestamp":1638178841000},"page":"e246359","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Anaesthetic challenges in the spine surgery of a young Asian man with lumbar amyloidosis"],"prefix":"10.1136","volume":"14","author":[{"given":"Jabraan","family":"Jamil","sequence":"first","affiliation":[{"name":"Anaesthesia and Intensive Care Unit, Hospital Queen Elizabeth, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chong Yan","family":"Tay","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Melaka General Hospital, Melaka, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chin Pei","family":"Bong","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Hospital Queen Elizabeth, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2517-597X","authenticated-orcid":false,"given":"Tat Boon","family":"Yeap","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,11,29]]},"reference":[{"key":"2025082701375512000_14.11.e246359.1","doi-asserted-by":"crossref","DOI":"10.2147\/CLEP.S39981","article-title":"Systemic AA amyloidosis: epidemiology, diagnosis, and management","volume":"6","author":"de As\u00faa","year":"2014","journal-title":"Clin Epidemiol"},{"key":"2025082701375512000_14.11.e246359.2","doi-asserted-by":"publisher","DOI":"10.1258\/acb.2011.011225"},{"key":"2025082701375512000_14.11.e246359.3","unstructured":"Kyle RA , Linos A , Beard CM , et al . 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