{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T04:38:31Z","timestamp":1771303111727,"version":"3.50.1"},"reference-count":12,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,12,31]]},"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:p>Bleeding nasal mass in adolescent boys has customarily been attributed to Juvenile nasopharyngeal angiofibroma. However, little is known regarding the extranasopharyngeal origin of angiofibroma, as highlighted in this case report of a 15-year-old boy who presented with recurrent epistaxis and nasal obstruction. On constructing a working diagnosis of nasal haemangioma, the patient was taken up for endoscopic excision under general anaesthesia. Intraoperative endoscopic findings and histopathological examination revealed the diagnosis of middle turbinate angiofibroma, which is an extremely rare extranasopharyngeal angiofibroma. Consequently, this represents the third described case of a juvenile angiofibroma arising from the middle turbinate.<\/jats:p>","DOI":"10.1136\/bcr-2021-246490","type":"journal-article","created":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T11:35:34Z","timestamp":1644233734000},"page":"e246490","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Middle turbinate angiofibroma in an adolescent boy"],"prefix":"10.1136","volume":"15","author":[{"given":"Mohamed Faizal","family":"Hassan","sequence":"first","affiliation":[{"name":"Department of ENT, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5261-3798","authenticated-orcid":false,"given":"Kezevino","family":"Nagi","sequence":"additional","affiliation":[{"name":"Department of ENT, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil Kumar","family":"Saxena","sequence":"additional","affiliation":[{"name":"Department of ENT, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bheemanathi Hanuman","family":"Srinivas","sequence":"additional","affiliation":[{"name":"Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,2,7]]},"reference":[{"key":"2025082622521325000_15.2.e246490.1","first-page":"1122","article-title":"Expression of androgen receptors in nasopharyngeal angiofibroma: an immunohistochemical study of 24 cases","volume":"11","author":"Hwang","year":"1998","journal-title":"Mod Pathol"},{"key":"2025082622521325000_15.2.e246490.2","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0165-5876(00)00404-3","article-title":"Extranasopharyngeal angiofibroma","volume":"56","author":"Huang","year":"2000","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"2025082622521325000_15.2.e246490.3","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.bjorl.2015.10.019","article-title":"Middle turbinate angiofibroma: an unusual location for juvenile angiofibroma","volume":"84","author":"Toplu","year":"2018","journal-title":"Braz J Otorhinolaryngol"},{"key":"2025082622521325000_15.2.e246490.4","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/coa.12939","article-title":"Extranasopharyngeal angiofibroma revisited","volume":"43","author":"Windfuhr","year":"2018","journal-title":"Clin Otolaryngol"},{"key":"2025082622521325000_15.2.e246490.5","doi-asserted-by":"crossref","first-page":"269","DOI":"10.12968\/hosp.2004.65.5.13701","article-title":"New aspects of pathogenesis of juvenile angiofibroma","volume":"65","author":"Schick","year":"2004","journal-title":"Hosp Med"},{"key":"2025082622521325000_15.2.e246490.6","doi-asserted-by":"publisher","DOI":"10.1097\/00125480-200007010-00006"},{"key":"2025082622521325000_15.2.e246490.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64054-0"},{"key":"2025082622521325000_15.2.e246490.8","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3109\/00016489.2014.952774","article-title":"Hormonal receptors and vascular endothelial growth factor in juvenile nasopharyngeal angiofibroma: immunohistochemical and tissue microarray analysis","volume":"135","author":"Liu","year":"2015","journal-title":"Acta Otolaryngol"},{"key":"2025082622521325000_15.2.e246490.9","doi-asserted-by":"crossref","unstructured":"Assiri KS , Al-Ahmari MS , Alshahrani MS , et al . Clinical and pathological features of angiomatous nasal polyps: a report of four cases and review of literature. Cureus.doi:10.7759\/cureus.7642","DOI":"10.7759\/cureus.7642"},{"key":"2025082622521325000_15.2.e246490.10","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.pedex.2006.05.007","article-title":"Autoamputation of an extranasopharyngeal angiofibroma of the nasal septum","volume":"1","author":"Castillo","year":"2006","journal-title":"Int J Pediatr Otorhinolaryngol Extra"},{"key":"2025082622521325000_15.2.e246490.11","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1908"},{"key":"2025082622521325000_15.2.e246490.12","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jobcr.2015.04.001","article-title":"Solitary fibrous tumor of the nasal cavity and paranasal sinuses: a case report","volume":"5","author":"Zieli\u0144ska-Ka\u017amierska","year":"2015","journal-title":"J Oral Biol Craniofacial Res"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-246490","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T05:52:18Z","timestamp":1756273938000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-246490"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":12,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,2,7]]},"published-print":{"date-parts":[[2022,2]]}},"alternative-id":["10.1136\/bcr-2021-246490"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-246490","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2]]}}}