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However, to salvage the limb with thrombolysis, an interventional radiology angiogram was performed. The angiogram demonstrated diffuse arterial spasm and response to nitroglycerin. She was treated with nitroglycerin drip and transitioned to a calcium channel blocker. She did improve significantly. To ensure no embolic sequelae, the patient was discharged with a month of oral anticoagulation.<\/jats:p>","DOI":"10.1136\/bcr-2021-246495","type":"journal-article","created":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T11:36:35Z","timestamp":1641468995000},"page":"e246495","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Acute limb ischaemia due to vasospasm: a rare presentation"],"prefix":"10.1136","volume":"15","author":[{"given":"Raed","family":"Al Yacoub","sequence":"first","affiliation":[{"name":"Department of Medicine, University of Florida, Gainesville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaymin","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Florida, Gainesville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neha","family":"Solanky","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Florida, Gainesville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7666-356X","authenticated-orcid":false,"given":"Nila S","family":"Radhakrishnan","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Florida, Gainesville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,1,6]]},"reference":[{"key":"2025082710005135000_15.1.e246495.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.12.037"},{"key":"2025082710005135000_15.1.e246495.2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1998.00884.x"},{"key":"2025082710005135000_15.1.e246495.3","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800760527"},{"key":"2025082710005135000_15.1.e246495.4","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(86)90161-3"},{"key":"2025082710005135000_15.1.e246495.5","doi-asserted-by":"publisher","DOI":"10.1177\/1538574415596740"},{"key":"2025082710005135000_15.1.e246495.6","doi-asserted-by":"publisher","DOI":"10.1111\/jth.12181"},{"key":"2025082710005135000_15.1.e246495.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2006.08.001"},{"key":"2025082710005135000_15.1.e246495.8","first-page":"165","article-title":"Ergotamine-Induced lower extremity arterial vasospasm presenting as acute limb ischemia","volume":"16","author":"Demir","year":"2010","journal-title":"Diagn Interv Radiol"},{"key":"2025082710005135000_15.1.e246495.9","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1177\/000331970105200509","article-title":"St. Anthony's fire (ergotamine induced leg ischemia)--a case report and review of the literature","volume":"52","author":"Zavaleta","year":"2001","journal-title":"Angiology"},{"key":"2025082710005135000_15.1.e246495.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2008.05.008"},{"key":"2025082710005135000_15.1.e246495.11","doi-asserted-by":"publisher","DOI":"10.1177\/0003319706291154"},{"key":"2025082710005135000_15.1.e246495.12","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3400\/avd.cr.13-00113","article-title":"Vasospastic limb ischemia presenting acute and chronic limb ischemia","volume":"7","author":"Kaneyama","year":"2014","journal-title":"Ann Vasc Dis"},{"key":"2025082710005135000_15.1.e246495.13","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-10-0292"},{"key":"2025082710005135000_15.1.e246495.14","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-10-74-0802"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-246495","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:00:58Z","timestamp":1756314058000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-246495"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1,6]]},"published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1136\/bcr-2021-246495"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-246495","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2022,1]]}}}