{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T10:32:39Z","timestamp":1772793159456,"version":"3.50.1"},"reference-count":41,"publisher":"BMJ","issue":"11","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/bmj.com\/coronavirus\/usage"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,10,25]]},"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:p>Patients with SARS-CoV-2 pneumonia can suffer from pneumothorax and persistent air leak (PAL). The pneumothorax occurs with or without pre-existing lung disease. PAL refers to air leak lasting more than 5\u20137\u2009days and arises due to bronchopleural or alveolopleural fistula. The management of PAL can be challenging as a standard management guideline is lacking. Here we present the case of a 42-year-old smoker with COVID-19 who presented to the hospital with fever, cough, acute left-sided chest pain and shortness of breath. He suffered from a large left-sided pneumothorax requiring immediate chest tube drainage. Unfortunately, the air leak persisted for 13 days before one-way endobronchial valve (EBV) was used with complete resolution of the air leak. We also review the literature regarding other cases of EBV utilisation for PAL in patients with COVID-19.<\/jats:p>","DOI":"10.1136\/bcr-2021-246671","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T10:36:50Z","timestamp":1637318210000},"page":"e246671","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Successful use of endobronchial valve for persistent air leak in a patient with COVID-19 and bullous emphysema"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3595-8804","authenticated-orcid":false,"given":"Biplab K","family":"Saha","sequence":"first","affiliation":[{"name":"Pulmonary and Critical Care Medicine, Ozarks Medical Center, West Plains, Missouri, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyssa","family":"Bonnier","sequence":"additional","affiliation":[{"name":"Department of Nursing, Goldfarb School of Nursing at Barnes-Jewish College, St Louis, Missouri, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2070-3585","authenticated-orcid":false,"given":"Woon Hean","family":"Chong","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care Medicine, Albany Medical Center, Albany, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Praveen","family":"Chenna","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care Medicine, Washington University School of Medicine in Saint Louis, St Louis, Missouri, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,11,19]]},"reference":[{"key":"2025082711371896000_14.11.e246671.1","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1164\/rccm.201902-0383OC","article-title":"Improving lung function in severe heterogenous emphysema with the Spiration valve system (EMPROVE). 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