{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:53:30Z","timestamp":1791420810392,"version":"4.3.3"},"reference-count":8,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,1,21]]},"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:p>Primary pleural liposarcoma (PPL) is a rare primary malignant pleural tumour originating from primitive mesenchymal tissue. We report the case of a 25-year-old man with a 6-week history of shortness of breath, cough, chest pain and hoarseness of voice. Chest X-ray showed a left opacified hemithorax, and thoracic CT scan revealed a large, heterogeneous, hypodense mass in the left hemithorax. The patient was taken up for ultrasound-guided core biopsy of the mass lesion, and histopathological examination revealed the diagnosis as a pleomorphic variant of PPL. We highlight the importance of considering PPL as a differential diagnosis in cases of large hemithoracic masses.<\/jats:p>","DOI":"10.1136\/bcr-2021-246683","type":"journal-article","created":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T11:32:00Z","timestamp":1645788720000},"page":"e246683","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Primary pleural liposarcoma: a rare differential for an opaque hemithorax"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4264-0706","authenticated-orcid":false,"given":"Avishek","family":"Layek","sequence":"first","affiliation":[{"name":"Pulmonary Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akhlesh","family":"Rajpoot","sequence":"additional","affiliation":[{"name":"Pulmonary Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashant","family":"Joshi","sequence":"additional","affiliation":[{"name":"Pathology & Laboratory Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7982-6267","authenticated-orcid":false,"given":"Mayank","family":"Mishra","sequence":"additional","affiliation":[{"name":"Pulmonary Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,2,25]]},"reference":[{"key":"2025082622444905000_15.2.e246683.1","doi-asserted-by":"crossref","first-page":"438","DOI":"10.4103\/lungindia.lungindia_246_18","article-title":"Primary pleural liposarcoma: a rare entity","volume":"36","author":"Prabhakar","year":"2019","journal-title":"Lung India"},{"key":"2025082622444905000_15.2.e246683.2","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.20.4.g00jl021007"},{"key":"2025082622444905000_15.2.e246683.3","first-page":"E166","article-title":"Primary pleural liposarcoma, pleomorphic variant.","volume":"6","author":"Carrillo B","year":"2014","journal-title":"J Thorac Dis"},{"key":"2025082622444905000_15.2.e246683.4","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200205000-00006"},{"key":"2025082622444905000_15.2.e246683.5","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/S0025-6196(12)61792-3","article-title":"Liposarcoma of the pleura","volume":"69","author":"Wong","year":"1994","journal-title":"Mayo Clin Proc"},{"key":"2025082622444905000_15.2.e246683.6","doi-asserted-by":"crossref","first-page":"699","DOI":"10.5858\/2000-124-0699-LOTPC","article-title":"Liposarcoma of the pleural cavity: clinical and pathologic features of 4 cases with a review of the literature","volume":"124","author":"Okby","year":"2000","journal-title":"Arch Pathol Lab Med"},{"key":"2025082622444905000_15.2.e246683.7","first-page":"45","volume-title":"WHO classification of tumours editorial board. soft tissue and bone tumours","volume":"3","author":"Pedeutour","year":"2020"},{"key":"2025082622444905000_15.2.e246683.8","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1055\/s-2000-6888","article-title":"Primary myxoid sarcoma of the pleura: 5 years follow-up","volume":"48","author":"Tosson","year":"2000","journal-title":"Thorac Cardiovasc Surg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-246683","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T05:44:57Z","timestamp":1756273497000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-246683"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":8,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,2,25]]},"published-print":{"date-parts":[[2022,2]]}},"alternative-id":["10.1136\/bcr-2021-246683"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-246683","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2]]}}}