{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:05:52Z","timestamp":1756339552798,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,12,30]]},"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:p>Sweet\u2019s syndrome (acute febrile neutrophilic dermatosis) is a rare disorder of unclear aetiology characterised by painful cutaneous lesions, sometimes accompanied by systemic symptoms. It has been associated with several autoimmune conditions, drugs, malignancies and infections, though many cases are idiopathic. We describe a case of Sweet\u2019s syndrome in a 49-year-old man with pre-existing psoriasis following recent initiation of risankizumab therapy. There are very few reported cases of Sweet\u2019s syndrome in association with psoriasis and no existing reports in association with an IL-23 inhibiting medication. Further investigation of the potentially overlapping immunologic pathways implicated in cutaneous reactions to biologic agents and autoimmune conditions such as psoriasis may yield insights into the pathogenesis of such conditions and guide advancements in the rapidly evolving field of targeted biologic therapies.<\/jats:p>","DOI":"10.1136\/bcr-2021-246774","type":"journal-article","created":{"date-parts":[[2022,2,8]],"date-time":"2022-02-08T12:05:44Z","timestamp":1644321944000},"page":"e246774","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Sweet\u2019s syndrome in the setting of newly initiated risankizumab therapy for pre-existing psoriasis"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0128-0502","authenticated-orcid":false,"given":"Fadwa","family":"Ahmed","sequence":"first","affiliation":[{"name":"Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Masur","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Internal Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaza","family":"Ben Khadra","sequence":"additional","affiliation":[{"name":"Department of Pathology, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7825-062X","authenticated-orcid":false,"given":"Muhammad","family":"Baig","sequence":"additional","affiliation":[{"name":"Department of Medicine, Miriam Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,2,8]]},"reference":[{"key":"2025082710360353000_15.2.e246774.1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-2-34"},{"key":"2025082710360353000_15.2.e246774.2","first-page":"1081","article-title":"Sweet\u2019s syndrome: diagnostic criteria revisited","volume":"15","author":"Nofal","year":"2017","journal-title":"JDDG: Journal der Deutschen Dermatologischen Gesellschaft"},{"key":"2025082710360353000_15.2.e246774.3","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s42466-019-0041-1","article-title":"Neuro-Sweet syndrome - a rare differential diagnosis in aseptic meningoencephalitis","volume":"1","author":"Hoffmann","year":"2019","journal-title":"Neurol Res Pract"},{"key":"2025082710360353000_15.2.e246774.4","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s13760-016-0695-1","article-title":"Neuro sweet syndrome: a systematic review. 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