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The patient was treated with valaciclovir for 14 days and cefradine for 7 days (due to the possibility of secondary bacterial infection). Significant symptomatic improvement was noted after 1 week. The 1-year follow-up was unremarkable. According to our knowledge and review of the literature, this is one of the few cases reported of vulvar herpes zoster, especially related to infliximab.<\/jats:p>","DOI":"10.1136\/bcr-2021-246797","type":"journal-article","created":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T05:25:19Z","timestamp":1640928319000},"page":"e246797","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Vulvar herpes zoster infection: a rare and challenging diagnosis"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5141-2852","authenticated-orcid":false,"given":"Matilde Matos","family":"Martins","sequence":"first","affiliation":[{"name":"Gynaecology and Obstetrics, Centro Hospitalar de Entre o Douro e Vouga EPE, Santa Maria da Feira, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Gynaecology and Obstetrics, Centro Hospitalar de Entre o Douro e Vouga EPE, Santa Maria da Feira, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel","family":"Maciel","sequence":"additional","affiliation":[{"name":"Gynaecology and Obstetrics, Centro Hospitalar de Entre o Douro e Vouga EPE, Santa Maria da Feira, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Costa","sequence":"additional","affiliation":[{"name":"Gynaecology and Obstetrics, Centro Hospitalar de Entre o Douro e Vouga EPE, Santa Maria da Feira, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,12,31]]},"reference":[{"key":"2025082713090368000_14.12.e246797.1","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.2147\/JPR.S199124","article-title":"Sacral (S1) herpes zoster","volume":"12","author":"Chiriac","year":"2019","journal-title":"J Pain Res"},{"key":"2025082713090368000_14.12.e246797.2","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.clinmicnews.2018.09.001","article-title":"Genital zoster infection: the great imposter","volume":"40","author":"Granato","year":"2018","journal-title":"Clin Microbiol Newsl"},{"key":"2025082713090368000_14.12.e246797.3","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1086\/510206","article-title":"Recommendations for the management of herpes zoster","volume":"44 Suppl 1","author":"Dworkin","year":"2007","journal-title":"Clin Infect Dis"},{"key":"2025082713090368000_14.12.e246797.4","doi-asserted-by":"crossref","unstructured":"Magdaleno-Tapial J et al . 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