{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:06:14Z","timestamp":1756339574103,"version":"3.44.0"},"reference-count":29,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,1,13]]},"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:p>Parathyroid carcinoma is very rare in pregnancy. Clinical features are similar to primary hyperparathyroidism. A 38-year-old pregnant woman had repeated hospital admissions for palpitations, headaches, dizziness and polydipsia. Blood investigations showed severe hypercalcaemia with raised parathyroid hormone and 24-hour ECG showed ventricular bigeminy and premature ventricular contractions. Neck ultrasound showed a lesion in the right thyroid lobe. Consequently, she underwent an en bloc resection of the right parathyroid and thyroid lobe at 23 weeks gestation. Histology results confirmed parathyroid cancer. This case highlights the complexities of identifying hypercalcaemia in pregnancy due to the overlapping features with common disorders of pregnancy. Early recognition and timely surgical management can prevent maternal and fetal complications. Also, the case demonstrates the value of interprofessional collaboration between different specialities in providing quality care and improving outcomes. An abridged version of this case was presented at European Congress of Endocrinology 2021.<\/jats:p>","DOI":"10.1136\/bcr-2021-247069","type":"journal-article","created":{"date-parts":[[2022,2,8]],"date-time":"2022-02-08T12:07:29Z","timestamp":1644322049000},"page":"e247069","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Parathyroid carcinoma presenting with ventricular bigeminy in pregnancy"],"prefix":"10.1136","volume":"15","author":[{"given":"Leher","family":"Gumber","sequence":"first","affiliation":[{"name":"Nottingham University Hospitals NHS Trust, Nottingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6664-8550","authenticated-orcid":false,"given":"Karthikeyan","family":"Sivasankaran","sequence":"additional","affiliation":[{"name":"Sherwood Forest Hospitals NHS Foundation Trust, Sutton-In-Ashfield, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sardar Mohammad Shoaib","family":"Khan","sequence":"additional","affiliation":[{"name":"Sherwood Forest Hospitals NHS Foundation Trust, Sutton-In-Ashfield, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,2,8]]},"reference":[{"key":"2025082711153793000_15.2.e247069.1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2010.10.013"},{"key":"2025082711153793000_15.2.e247069.2","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.clon.2010.04.007","article-title":"Parathyroid carcinoma","volume":"22","author":"Givi","year":"2010","journal-title":"Clin Oncol"},{"key":"2025082711153793000_15.2.e247069.3","doi-asserted-by":"crossref","DOI":"10.1186\/s12902-019-0368-1","article-title":"Current concepts in parathyroid carcinoma: a single centre experience","volume":"19","author":"Ferraro","year":"2019","journal-title":"BMC Endocr Disord"},{"key":"2025082711153793000_15.2.e247069.4","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196904000-00022"},{"key":"2025082711153793000_15.2.e247069.5","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5182"},{"key":"2025082711153793000_15.2.e247069.6","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19990801)86:3<538::AID-CNCR25>3.0.CO;2-K"},{"key":"2025082711153793000_15.2.e247069.7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2011.01391.x"},{"key":"2025082711153793000_15.2.e247069.8","doi-asserted-by":"crossref","first-page":"198","DOI":"10.4103\/2230-8210.119570","article-title":"Parathyroid carcinoma masquerading as morning sickness in pregnancy","volume":"17","author":"Panchani","year":"2013","journal-title":"Indian J Endocrinol Metab"},{"key":"2025082711153793000_15.2.e247069.9","doi-asserted-by":"crossref","first-page":"151","DOI":"10.12998\/wjcc.v2.i5.151","article-title":"Parathyroid carcinoma in pregnancy","volume":"2","author":"Bareti\u0107","year":"2014","journal-title":"World J Clin Cases"},{"key":"2025082711153793000_15.2.e247069.10","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-2977(98)00010-2"},{"key":"2025082711153793000_15.2.e247069.11","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1002\/ccr3.646","article-title":"Hypercalcemia in pregnancy - 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