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A teenager from a low socioeconomic status family, with longstanding weight loss, polyphagia, polyuria, vomiting and abdominal pain, attended the emergency department, also complaining of anosmia and odynophagia. He was diagnosed with COVID-19 and new-onset DKA. The second child had 2\u2009weeks of diabetes symptoms and was admitted with new-onset mild DKA. SARS-CoV-2 RT-PCR test was positive, although asymptomatic. Persistent hyperglycaemia with high insulin requirements was a common feature to both patients. Both cases support that SARS-CoV-2 may have an association with rapidly increasing insulin daily needs. In case one, not only fear of COVID-19 delayed hospital attendance but also the setting of a low socioeconomic status family appears to have enhanced the risk for late diagnosis and challenging disease management.<\/jats:p>","DOI":"10.1136\/bcr-2021-247309","type":"journal-article","created":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T11:11:52Z","timestamp":1642504312000},"page":"e247309","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["COVID-19 in two children with new-onset diabetes: case reports"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5735-7332","authenticated-orcid":false,"given":"Ana","family":"Lan\u00e7a","sequence":"first","affiliation":[{"name":"Pediatrics Department, Hospital de S\u00e3o Francisco Xavier, Centro Hospitalar de Lisboa Ocidental EPE, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e1udia","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Hospital de Torres Novas, Centro Hospitalar do M\u00e9dio Tejo EPE, Santarem, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catarina","family":"Diamantino","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Endocrinology Unit, Hospital Dona Estef\u00e2nia, Centro Hospitalar Universit\u00e1rio de Lisboa Central, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Laura","family":"Fitas","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Endocrinology Unit, Hospital Dona Estef\u00e2nia, Centro Hospitalar Universit\u00e1rio de Lisboa Central, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,1,18]]},"reference":[{"key":"2025082712320243000_15.1.e247309.1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d4092"},{"key":"2025082712320243000_15.1.e247309.2","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1111\/pedi.13084","article-title":"COVID-19 outbreak and pediatric diabetes: perceptions of health care professionals worldwide","volume":"21","author":"Elbarbary","year":"2020","journal-title":"Pediatr Diabetes"},{"key":"2025082712320243000_15.1.e247309.3","unstructured":"Galhardo J , Monteiro AC , Martins AS . 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