{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:03:34Z","timestamp":1756425814386,"version":"3.44.0"},"reference-count":13,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,2,24]]},"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:p>The SARS-CoV-2 virus has caused a global pandemic with serious impact around the world. Patients most commonly present with severe lung involvement and acute respiratory failure; however, multisystem inflammatory syndrome in adults (MIS-A) is a known\u2014although rare\u2014complication. We present a case of a 49-year-old patient who presented with combined cardiogenic and vasodilatory shock and was diagnosed with MIS-A. He initially required venoarterial extracorporeal membrane oxygenation and Impella for haemodynamic support but was able to be weaned off these devices with complete recovery of left ventricular systolic function. This case demonstrates that MIS-A may present as haemodynamic collapse in adults, but complete recovery is possible with proper haemodynamic support.<\/jats:p>","DOI":"10.1136\/bcr-2021-247427","type":"journal-article","created":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T10:50:32Z","timestamp":1646650232000},"page":"e247427","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Multisystem inflammatory syndrome in adults (MIS-A) following COVID-19 requiring venoarterial extracorporeal membrane oxygenation"],"prefix":"10.1136","volume":"15","author":[{"given":"Seth","family":"Newman","sequence":"first","affiliation":[{"name":"Department of Medicine, Montefiore Medical Center, Bronx, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengwei","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Medicine, Montefiore Medical Center, Bronx, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shivank","family":"Madan","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Montefiore Medical Center, Bronx, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Sims","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Montefiore Medical Center, Bronx, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,3,7]]},"reference":[{"key":"2025082802250714000_15.3.e247427.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021680"},{"key":"2025082802250714000_15.3.e247427.2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6940e1"},{"key":"2025082802250714000_15.3.e247427.3","unstructured":"Newman SB . Audio file of patient consent [sound recording]. Created October 13, 2021."},{"key":"2025082802250714000_15.3.e247427.4","unstructured":"CDC.gov [internet] . Multisystem inflammatory syndrome in adults (MIS-A) case definition information for healthcare providers. Available: https:\/\/www.cdc.gov\/mis\/mis-a\/hcp.html [Accessed 31 Dec 2021]."},{"key":"2025082802250714000_15.3.e247427.5","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-021-04843-1"},{"key":"2025082802250714000_15.3.e247427.6","doi-asserted-by":"crossref","first-page":"e182","DOI":"10.1111\/jdv.17841","article-title":"Multisystem inflammatory syndrome in adults (MIS-A): a new addition to COVID-19 puzzle","volume":"36","author":"Hajra","year":"2022","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2025082802250714000_15.3.e247427.7","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1016\/j.jcmg.2020.05.003","article-title":"COVID-19 \"Fulminant Myocarditis\" Successfully Treated With Temporary Mechanical Circulatory Support","volume":"13","author":"Salamanca","year":"2020","journal-title":"JACC Cardiovasc Imaging"},{"key":"2025082802250714000_15.3.e247427.8","doi-asserted-by":"crossref","DOI":"10.1093\/ehjcr\/ytaa523","article-title":"Fulminant myocarditis in a COVID-19 positive patient treated with mechanical circulatory support - a case\u00a0report","volume":"5","author":"Papageorgiou","year":"2021","journal-title":"Eur Heart J Case Rep"},{"key":"2025082802250714000_15.3.e247427.9","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1097\/MAT.0000000000001178","article-title":"First successful treatment of coronavirus disease 2019 induced refractory cardiogenic plus Vasoplegic shock by combination of percutaneous ventricular assist device and extracorporeal membrane oxygenation: a case report","volume":"66","author":"Bemtgen","year":"2020","journal-title":"Asaio J"},{"key":"2025082802250714000_15.3.e247427.10","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2021-242034","article-title":"COVID-19-associated inflammatory syndrome in an adult woman with unexplained multiple organ failure: staying vigilant for COVID-19 complications as the pandemic surges","volume":"14","author":"Veyseh","year":"2021","journal-title":"BMJ Case Rep"},{"key":"2025082802250714000_15.3.e247427.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2014.07.090"},{"key":"2025082802250714000_15.3.e247427.12","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1002\/art.41454","article-title":"American College of rheumatology clinical guidance for multisystem inflammatory syndrome in children associated with SARS-CoV-2 and Hyperinflammation in pediatric COVID-19: version 1","volume":"72","author":"Henderson","year":"2020","journal-title":"Arthritis Rheumatol"},{"key":"2025082802250714000_15.3.e247427.13","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ijid.2021.05.050","article-title":"Multisystem inflammatory syndrome in adults: a rare sequela of SARS-CoV-2 infection","volume":"108","author":"Ahmad","year":"2021","journal-title":"Int J Infect Dis"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-247427","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:25:17Z","timestamp":1756373117000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-247427"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":13,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,3,7]]},"published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1136\/bcr-2021-247427"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-247427","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2022,3]]}}}