{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T09:29:48Z","timestamp":1784366988006,"version":"3.55.0"},"reference-count":31,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,5,5]]},"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p>Struma ovarii (SO) is an uncommon monodermal teratoma predominantly composed of mature thyroid tissue. Approximately 5% of SO are malignant; however, metastases are rare. A single female in her 40s, with a medical history of Graves\u2019 disease and bilateral cystectomy 10 years prior for right endometriotic cyst and left SO, presented with an enlarging abdominal mass for 4\u2009months. Ultrasound pelvis showed a 13.8\u2009cm left adnexal heterogeneous solid-cystic mass with internal septations and vascularity. She underwent open left salpingo-oophorectomy and resection of fibrous nodules from the right infundibulo-pelvic ligament and fallopian tube. Histology showed highly differentiated metastatic follicular carcinoma. She subsequently underwent total thyroidectomy, total hysterectomy, right salpingo-oophorectomy, tumour debulking and omentectomy followed by radioactive iodine treatment. Four-year follow-up did not show tumour recurrence or metastases. Due to its rarity, there are no well-established guidelines for the management and follow-up of metastatic follicular carcinoma arising from SO.<\/jats:p>","DOI":"10.1136\/bcr-2021-247697","type":"journal-article","created":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T13:43:35Z","timestamp":1653313415000},"page":"e247697","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Metastatic follicular carcinoma arising from struma ovarii"],"prefix":"10.1136","volume":"15","author":[{"given":"Jia","family":"Deng","sequence":"first","affiliation":[{"name":"Obstetrics & Gynaecology, KK Women's and Children's Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang Huang Grace","family":"Ng","sequence":"additional","affiliation":[{"name":"Obstetrics & Gynaecology, Maternal Fetal Medicine, KK Women's and Children's Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Hock","family":"Chew","sequence":"additional","affiliation":[{"name":"Pathology & Laboratory Medicine, KK Women's and Children's Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Kuei","family":"Lim","sequence":"additional","affiliation":[{"name":"Obstetrics & Gynaecology, Gynaecological Oncology, KK Women's and Children's Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,5,17]]},"reference":[{"key":"2025082701562015000_15.5.e247697.1","unstructured":"Ling A , Foo LL , Lee E . 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