{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T23:21:23Z","timestamp":1793748083957,"version":"4.6.1"},"reference-count":14,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,4,27]]},"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p>A woman in her 30s presented with progressive worsening of dyspnoea for 6 months. On evaluation, she was diagnosed with severe rheumatic mitral stenosis (mitral valve area of 0.6\u2009cm<jats:sup>2<\/jats:sup>) and a large ostium secundum atrial septal defect (21\u2009mm) with a left to right shunt and severe pulmonary artery hypertension. She was diagnosed with Lutembacher syndrome and was evaluated for suitability of a percutaneous approach. She was subjected to a combined procedure of percutaneous transluminal mitral commissurotomy followed by device closure of the atrial septal defect. The patient tolerated the procedure, remained haemodynamically stable and was discharged after 4\u2009days. This procedure can prevent the morbidity and mortality associated with anaesthesia and cardiac surgery and the psychological trauma of a thoracotomy scar particularly in a female patient, as well as obviate the need for prolonged hospital stay.<\/jats:p>","DOI":"10.1136\/bcr-2021-247984","type":"journal-article","created":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T11:40:28Z","timestamp":1652874028000},"page":"e247984","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Non-surgical treatment of Lutembacher syndrome: combined percutaneous transcatheter therapy"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4922-2806","authenticated-orcid":false,"given":"Dilip","family":"Johny","sequence":"first","affiliation":[{"name":"Cardiology, KS Hegde Medical Academy, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kodangala","family":"Subramanyam","sequence":"additional","affiliation":[{"name":"Cardiology, KS Hegde Medical Academy, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram Mohan","family":"Bhandary","sequence":"additional","affiliation":[{"name":"Internal Medicine, KS Hegde Medical Academy, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amita","family":"Rao","sequence":"additional","affiliation":[{"name":"Periodontology, AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,5,18]]},"reference":[{"key":"2025082711362086000_15.5.e247984.1","unstructured":"Perloff JK . The clinical recognition of congenital heart disease. 4th ed. Philadelphia: Saunders, 1994: pp. 323."},{"key":"2025082711362086000_15.5.e247984.2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320530113"},{"key":"2025082711362086000_15.5.e247984.3","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1067\/mje.2001.111265","article-title":"Giant left atrium secondary to tight mitral stenosis leading to acquired Lutembacher syndrome: a case report with emphasis on role of echocardiography in assessment of Lutembacher syndrome","volume":"14","author":"Ananthasubramaniam","year":"2001","journal-title":"J Am Soc Echocardiogr"},{"key":"2025082711362086000_15.5.e247984.4","doi-asserted-by":"crossref","unstructured":"Nagamani AC , Nagesh CM . Lutembacher syndrome (Ch.64) in a comprehensive approach to congenital heart diseases. Jaypee Brothers Medical Publisher, 2013: 908\u201316.","DOI":"10.5005\/jp\/books\/12075_64"},{"key":"2025082711362086000_15.5.e247984.5","first-page":"237","article-title":"De la stenose mitral avec communication interauriculaire","volume":"9","author":"Lutembacher","year":"1916","journal-title":"Arch Mal Coeur Vaiss"},{"key":"2025082711362086000_15.5.e247984.6","doi-asserted-by":"crossref","DOI":"10.1016\/0002-8703(87)90544-8","article-title":"Coexistent mitral valve disease with left-to-right shunt at the atrial level: clinical profile, hemodynamics, and surgical considerations in 67 consecutive patients","volume":"114","author":"Bashi","year":"1987","journal-title":"Am Heart J"},{"key":"2025082711362086000_15.5.e247984.7","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/0002-9149(58)90264-9","article-title":"Pathologic physiology of Lutembacher syndrome","volume":"2","author":"Sambhi","year":"1958","journal-title":"Am J Cardiol"},{"key":"2025082711362086000_15.5.e247984.8","unstructured":"Mahajan K , Oliver TI . Lutembacher syndrome. Treasure Island (FL): StatPearls Publishing, 2021. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK470307\/"},{"key":"2025082711362086000_15.5.e247984.9","first-page":"122","article-title":"Current diagnostic and treatment strategies for Lutembacher syndrome: the pivotal role of echocardiography","volume":"5","author":"Aminde","year":"2015","journal-title":"Cardiovasc Diagn Ther"},{"key":"2025082711362086000_15.5.e247984.10","first-page":"309","article-title":"Percutaneous closure of a secundum atrial septal defect and double balloon valvotomies of a severe mitral and aortic valve stenosis in a patient with Lutembacher's syndrome and severe pulmonary hypertension","volume":"25","author":"Ruiz","year":"1992","journal-title":"Cathet Cardiovasc Diagn"},{"key":"2025082711362086000_15.5.e247984.11","first-page":"199","article-title":"Definitive percutaneous treatment of Lutembacher's syndrome","volume":"48","author":"Joseph","year":"1999","journal-title":"Catheter Cardiovasc Interv"},{"key":"2025082711362086000_15.5.e247984.12","doi-asserted-by":"crossref","first-page":"385","DOI":"10.14740\/cr776w","article-title":"Combined percutaneous procedure in patient with Lutembacher syndrome: a case report and real-world experience review","volume":"9","author":"Phan","year":"2018","journal-title":"Cardiol Res"},{"key":"2025082711362086000_15.5.e247984.13","doi-asserted-by":"crossref","unstructured":"Alam MM , Khaled MFI . An Incidental Diagnosis of Rheumatic Mitral Stenosis and Secundum Atrial Septal Defect (Lutembacher\u2019s Syndrome) in a Young Woman. Case Rep Cardiol 2019.doi:10.1155\/2019\/9402987","DOI":"10.1155\/2019\/9402987"},{"key":"2025082711362086000_15.5.e247984.14","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00357-X"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-247984","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T18:36:31Z","timestamp":1756319791000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-247984"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":14,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,5,18]]},"published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1136\/bcr-2021-247984"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-247984","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5]]}}}