{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:43:21Z","timestamp":1756381401147,"version":"3.44.0"},"reference-count":18,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,10,14]]},"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:p>Chylous ascites is the accumulation of lymphatic fluid in the peritoneal cavity due to disruption of lymphatic drainage caused due to obstruction or trauma. We report a man in his 60s who was previously treated for diffuse large B cell lymphoma with radiation to bulky abdominal\/mesenteric lymphadenopathy. He was later found to have recurrent chylous ascites several years later, requiring multiple paracentesis. Recurrent lymphoma was ruled out with negative cytology of peritoneal fluid as well as lymph node biopsy with no evidence of malignancy. We believe that the patient had obstruction of lymphatic drainage due to previous radiation therapy causing fibrosis. The patient underwent lymphangiography which did not visualise the central lymphatic duct within the abdomen raising suspicion for obstruction of the ducts secondary to previous radiation.<\/jats:p>","DOI":"10.1136\/bcr-2021-248116","type":"journal-article","created":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T11:05:15Z","timestamp":1667214315000},"page":"e248116","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Recurrent chylous ascites in patient with previous retroperitoneal radiation treatment"],"prefix":"10.1136","volume":"15","author":[{"given":"Purva","family":"Sharma","sequence":"first","affiliation":[{"name":"Medical Oncology\/Hematology, East Tennessee State University-Quillen College of Medicine, Johnson City, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanishka","family":"Chakraborty","sequence":"additional","affiliation":[{"name":"Medical Oncology\/Hematology, East Tennessee State University-Quillen College of Medicine, Johnson City, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,10,31]]},"reference":[{"key":"2025082804041988000_15.10.e248116.1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1967.01330150031006"},{"key":"2025082804041988000_15.10.e248116.2","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.10-8-632"},{"key":"2025082804041988000_15.10.e248116.3","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.37358\/RC.18.7.6422","article-title":"Immunohistochemistry Particularities of retroperitoneal tumors","volume":"69","author":"Bratu","year":"2018","journal-title":"Rev Chim"},{"key":"2025082804041988000_15.10.e248116.4","doi-asserted-by":"crossref","first-page":"445","DOI":"10.37358\/RC.19.2.6932","article-title":"Vascular involvement in primary retroperitoneal tumors","volume":"70","author":"Marcu","year":"2019","journal-title":"Rev Chim"},{"key":"2025082804041988000_15.10.e248116.5","first-page":"5016","article-title":"Minimally invasive biopsy in retroperitoneal tumors (review)","volume":"4","author":"Marcu","year":"2019","journal-title":"Exp Ther Med"},{"key":"2025082804041988000_15.10.e248116.6","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2018-225140","article-title":"Primary intratracheal schwannoma resected during bronchoscopy using argon plasma coagulation","volume":"2018","author":"Sharma","year":"2018","journal-title":"BMJ Case Rep"},{"key":"2025082804041988000_15.10.e248116.7","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1990.01410140148027"},{"key":"2025082804041988000_15.10.e248116.8","first-page":"260","article-title":"Chylous ascites: diagnosis, causes and treatment","volume":"63","author":"Laterre","year":"2000","journal-title":"Acta Gastroenterol Belg"},{"key":"2025082804041988000_15.10.e248116.9","first-page":"183","article-title":"Chylous ascites in children","volume":"69","author":"Sanchez","year":"1971","journal-title":"Surgery"},{"key":"2025082804041988000_15.10.e248116.10","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/0360-3016(90)90554-W","article-title":"Chylous ascites after whole-abdomen irradiation for gynecologic malignancy","volume":"19","author":"Lentz","year":"1990","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2025082804041988000_15.10.e248116.11","first-page":"749","article-title":"Chylous ascites after radiation therapy for ovarian cancer","volume":"44","author":"Murray","year":"1974","journal-title":"Obstet Gynecol"},{"key":"2025082804041988000_15.10.e248116.12","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1006\/gyno.1996.0173","article-title":"Chemotherapy treatment of chyloperitoneum and peritoneal carcinomatosis due to cervical Cancer\u2014Review of literature","volume":"61","author":"Keung","year":"1996","journal-title":"Gynecol Oncol"},{"key":"2025082804041988000_15.10.e248116.13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/240473","article-title":"Chylous ascites: evaluation and management","volume":"2014","author":"Al-Busafi","year":"2014","journal-title":"ISRN Hepatol"},{"key":"2025082804041988000_15.10.e248116.14","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/64849421"},{"key":"2025082804041988000_15.10.e248116.15","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1097\/00004836-199012000-00021","article-title":"The management of postoperative chylous ascites. 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