{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:40:58Z","timestamp":1780472458579,"version":"3.54.1"},"reference-count":13,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,2,11]]},"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:p>This case discusses a 10-year-old boy who presented in significant respiratory distress with cardiac tamponade with associated gross ascites and hepatomegaly, requiring urgent transfer for pericardiocentesis. On further investigation, he was found to have multiple pulmonary emboli and evidence of panserositis. An underlying rheumatological cause was suspected in the absence of any evidence of infection or malignancy, and blood tests were positive for anti-double stranded DNA, anticardiolipin and antiglycoprotein antibodies as well as HLA B51. In his medical history, he has previously had mouth ulcers, chronic anaemia of undetermined cause and erythema multiforme. These symptoms, along with clinical presentation, mean a diagnosis of Behcet\u2019s disease and associated antiphospholipid syndrome was felt to be most likely. Anticoagulation therapy was commenced for treatment of the emboli, and colchicine was started for management of Behcet\u2019s disease. The patient was discharged clinically well from the hospital and continues under specialist rheumatological and haematological follow-up.<\/jats:p>","DOI":"10.1136\/bcr-2021-248134","type":"journal-article","created":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T11:17:57Z","timestamp":1646824677000},"page":"e248134","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Rare paediatric cardiopulmonary presentation of Behcet\u2019s disease"],"prefix":"10.1136","volume":"15","author":[{"given":"Rebecca","family":"Bradford-Duarte","sequence":"first","affiliation":[{"name":"Oliver Fisher Neonatal Unit, Medway Maritime Hospital, Gillingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Smith","sequence":"additional","affiliation":[{"name":"Neonatal Transfer Service, The Royal London Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jatinder","family":"Jheeta","sequence":"additional","affiliation":[{"name":"Paediatrics, Darent Valley Hospital, Dartford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,3,9]]},"reference":[{"key":"2025082712071304000_15.3.e248134.1","doi-asserted-by":"crossref","first-page":"108381","DOI":"10.1016\/j.clim.2020.108381","article-title":"Juvenile-onset Beh\u00e7et's syndrome and mimics","volume":"214","author":"Pain","year":"2020","journal-title":"Clin Immunol"},{"key":"2025082712071304000_15.3.e248134.2","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s00296-018-4208-9","article-title":"Diagnostic\/classification criteria in pediatric Beh\u00e7et's disease","volume":"39","author":"Batu","year":"2019","journal-title":"Rheumatol Int"},{"key":"2025082712071304000_15.3.e248134.3","doi-asserted-by":"crossref","unstructured":"Turkucar S , Dundar H , Acari C . 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