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The rarity of an almost synchronous manifestation of BIA-ALCL and breast carcinoma and the diagnostic challenges of mass-forming BIA-ALCL in a previously operated breast substantiate this report. The clinical course, diagnostic workup and therapeutic considerations are presented and discussed in detail. This case shows that a diagnosis of BIA-ALCL must always be considered even without a prosthesis in place in patients with a long history of textured implants.<\/jats:p>","DOI":"10.1136\/bcr-2021-248232","type":"journal-article","created":{"date-parts":[[2022,3,2]],"date-time":"2022-03-02T11:07:04Z","timestamp":1646219224000},"page":"e248232","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Anaplastic large cell lymphoma, ALK-negative of the breast diagnosed a short time after removal of breast implant in a patient with breast carcinoma: diagnostic and therapeutic considerations"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5160-9436","authenticated-orcid":false,"given":"Margit","family":"Riis","sequence":"first","affiliation":[{"name":"Department of Breast and Endocrine Surgery, Oslo University Hospital, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgy","family":"Csanaky","sequence":"additional","affiliation":[{"name":"Department of Pathology, Oslo University Hospital, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustav","family":"Lehne","sequence":"additional","affiliation":[{"name":"Department of Cancer Treatment, Oslo University Hospital, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aase","family":"Tangerud","sequence":"additional","affiliation":[{"name":"Department of Radiology, Oslo University Hospital, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,3,2]]},"reference":[{"key":"2025082711381343000_15.3.e248232.1","doi-asserted-by":"crossref","first-page":"554,555","DOI":"10.1097\/00006534-199708000-00065","article-title":"Anaplastic T-cell lymphoma in proximity to a saline-filled breast implant","volume":"100","author":"Keech","year":"1997","journal-title":"Plast Reconstr Surg"},{"key":"2025082711381343000_15.3.e248232.2","doi-asserted-by":"crossref","DOI":"10.1093\/jnci\/djw294","article-title":"Primary breast lymphoma in the United States: 1975-2013","volume":"109","author":"Thomas","year":"2017","journal-title":"J Natl Cancer Inst"},{"key":"2025082711381343000_15.3.e248232.3","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1111\/bjh.17194","article-title":"Uk guidelines on the diagnosis and treatment of breast implant-associated anaplastic large cell lymphoma on behalf of the medicines and healthcare products regulatory agency plastic, reconstructive and aesthetic surgery expert Advisory group","volume":"192","author":"Turton","year":"2021","journal-title":"Br J Haematol"},{"key":"2025082711381343000_15.3.e248232.4","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/85.11.892"},{"key":"2025082711381343000_15.3.e248232.5","unstructured":"Howlader NNA KM , Miller D , Brest A . 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