{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:10:11Z","timestamp":1756375811701,"version":"3.44.0"},"reference-count":20,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,2,25]]},"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:p>Gastrointestinal stromal tumours (GISTs) are very rare gastrointestinal (GI) mesenchymal tumours affecting only 0.02 children\/million\/year below the age of 14 years. We reported a 9-year-old girl presented to emergency department with pallor and haemoglobin of 50\u2009g\/L. Extensive workup for anaemia suggested iron-deficiency anaemia secondary to GI loss. Ultimately after blood transfusion of packed cells, she was discharged with a haemoglobin of 92\u2009g\/L with iron supplementation. Upper endoscopy showed incidental antral nodularity with biopsy proven helicobacter gastritis and an isolate 3\u20134\u2009cm suspicious mass in the lesser curvature. Abdomen imaging confirmed the gastric mass in addition to two lesions, one retroperitoneal and one paraspinal. She undergone open laparotomy with complete surgical resection of the gastric and retroperitoneal masses with histological confirmation of GIST and paraganglioma. This case emphasises the importance of proper examination of the stomach at endoscopy and to illustrate that although anaemia is common in paediatric age group it may be reflect serious medical condition even in normal looking child.<\/jats:p>","DOI":"10.1136\/bcr-2021-248365","type":"journal-article","created":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T11:17:13Z","timestamp":1646824633000},"page":"e248365","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["GIST presenting as refractory iron-deficiency anaemia in paediatric patient"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5568-3721","authenticated-orcid":false,"given":"Eman","family":"Al Atrash","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Gastroenterology, Sheikh Khalifa Medical City, Abu Dhabi, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Fahed","family":"Abdullah","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Oncology and Hematology, Sheikh Khalifa Medical City, Abu Dhabi, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1816-3281","authenticated-orcid":false,"given":"Joseph","family":"Pressey","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hematology and Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyam","family":"Mohan","sequence":"additional","affiliation":[{"name":"Department of Radiology, Sheikh Khalifa Medical City, Abu Dhabi, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,3,9]]},"reference":[{"key":"2025082802432519000_15.3.e248365.1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.canep.2015.10.031","article-title":"Global epidemiology of gastrointestinal stromal tumours (GIST): a systematic review of population-based cohort studies","volume":"40","author":"S\u00f8reide","year":"2016","journal-title":"Cancer Epidemiol"},{"key":"2025082802432519000_15.3.e248365.2","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.cancergen.2019.12.002","article-title":"Pediatric gastrointestinal stromal tumor: report of two novel patients harboring germline variants in SDHB and SdhC genes","volume":"241","author":"Rinelli","year":"2020","journal-title":"Cancer Genet"},{"key":"2025082802432519000_15.3.e248365.3","unstructured":"World Health Organization . 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