{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T10:50:09Z","timestamp":1783335009648,"version":"3.54.6"},"reference-count":30,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,2,8]]},"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:p>Nocardiosis is a rare opportunistic gram-positive bacterial infection. The genus <jats:italic>Nocardia<\/jats:italic> consists of non-motile, aerobic, non-spore-forming, catalase-positive, filamentous-branching bacteria with fragmentation into coccoid or bacillary forms. Opportunistic infections due to <jats:italic>Nocardia<\/jats:italic> are reported in immunocompromised patients. <jats:italic>Aspergillus fumigatus<\/jats:italic> is a conidia forming fungus that can be found in soil, plant matter and dust, causing invasive pulmonary and disseminated infection in immunocompromised patients. Both <jats:italic>Nocardia cyriacigeorgica<\/jats:italic> and <jats:italic>A. fumigatus<\/jats:italic> are known to cause pulmonary infection with metastatic dissemination to the central nervous system. We present a case of <jats:italic>Nocardia<\/jats:italic> and <jats:italic>Aspergillus<\/jats:italic> co-infection in a patient who presented within a few days of initiation of immunosuppressants for suspected systemic lupus erythematosus.<\/jats:p>","DOI":"10.1136\/bcr-2021-248381","type":"journal-article","created":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T11:48:42Z","timestamp":1646740122000},"page":"e248381","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Case of coexisting <i>Nocardia cyriacigeorgica<\/i> and <i>Aspergillus fumigatus<\/i> lung infection with metastatic disease of the central nervous system"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8206-3405","authenticated-orcid":false,"given":"Moni","family":"Roy","sequence":"first","affiliation":[{"name":"Internal Medicine, University of Illinois College of Medicine at Peoria, Peoria, Illinois, USA"},{"name":"OSF Saint Francis Medical Center, Peoria, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6969-0589","authenticated-orcid":false,"given":"Rone-Chun","family":"Lin","sequence":"additional","affiliation":[{"name":"Internal Medicine, Section of Infectious Diseases, University of Illinois college of medicine at Peoria, Peoria, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Joseph","family":"Farrell","sequence":"additional","affiliation":[{"name":"Internal Medicine, Section of Infectious Diseases, University of Illinois college of medicine at Peoria, Peoria, Illinois, USA"},{"name":"OSF System Laboratory, Peoria, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,3,8]]},"reference":[{"key":"2025082702052686000_15.3.e248381.1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.4.1496-1499.2002"},{"key":"2025082702052686000_15.3.e248381.2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.19.2.259-282.2006"},{"key":"2025082702052686000_15.3.e248381.3","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-51-4-1419"},{"key":"2025082702052686000_15.3.e248381.4","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.9.4895-4897.2005"},{"key":"2025082702052686000_15.3.e248381.5","first-page":"1","article-title":"Nocardia cyriacigeorgica brain abscess with pemphigus vulgaris: first report","volume":"30","author":"Benek","year":"2020","journal-title":"Br J Neurosurg"},{"key":"2025082702052686000_15.3.e248381.6","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.7.2.213"},{"key":"2025082702052686000_15.3.e248381.7","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198402000-00042"},{"key":"2025082702052686000_15.3.e248381.8","doi-asserted-by":"crossref","first-page":"omx061","DOI":"10.1093\/omcr\/omx061","article-title":"Nocardia cyriacigeorgica threatening an immunocompetent host; a rare case of paramediastinal abscess","volume":"2017","author":"Rivera","year":"2017","journal-title":"Oxf Med Case Reports"},{"key":"2025082702052686000_15.3.e248381.9","article-title":"A rare instance of simultaneous infection with disseminated Nocardia and pulmonary Aspergillus in a patient receiving treatment with ibrutinib for chronic lymphocytic leukemia","volume":"10","author":"Dotson","year":"2018","journal-title":"Cureus"},{"key":"2025082702052686000_15.3.e248381.10","doi-asserted-by":"crossref","DOI":"10.1002\/rcr2.392","article-title":"A case of Aspergillus and Nocardia infections after bronchial thermoplasty","volume":"7","author":"Matsubayashi","year":"2019","journal-title":"Respirol Case Rep"},{"key":"2025082702052686000_15.3.e248381.11","doi-asserted-by":"crossref","unstructured":"YL G , Zhu XY , Hu K , et al . 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