{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:40:21Z","timestamp":1756374021835,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,3,29]]},"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:p>An 18-month-old girl with hereditary hyaline fibromatosis syndrome (HHFS) and fixed flexion contractures presented with an oblique femur fracture, following a fall out of her mother\u2019s arms. The fracture was abutting intramedullary hyaline lesions. Due to her condition, balanced traction was impossible to apply. The authors report effective treatment of her injury using a non-operative approach in an early hip spica, over a 4-week period. There was no evidence of delayed osseous healing. Early spica application could be used as a definitive management option in children with femur fractures and fixed flexion contractures in future. This case emphasises the need for preventative measures to support bone health in patients with HHFS.<\/jats:p>","DOI":"10.1136\/bcr-2021-248447","type":"journal-article","created":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T11:56:05Z","timestamp":1649159765000},"page":"e248447","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Femur fracture in a paediatric patient with hereditary hyaline fibromatosis syndrome"],"prefix":"10.1136","volume":"15","author":[{"given":"Hannah Louise","family":"Morley","sequence":"first","affiliation":[{"name":"Trauma and Orthopaedics, Bradford Royal Infirmary, Bradford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David L","family":"Shaw","sequence":"additional","affiliation":[{"name":"Trauma and Orthopaedics, Bradford Royal Infirmary, Bradford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary","family":"Hannant","sequence":"additional","affiliation":[{"name":"Trauma and Orthopaedics, Bradford Royal Infirmary, Bradford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,4,5]]},"reference":[{"key":"2025082802082131000_15.4.e248447.1","doi-asserted-by":"crossref","DOI":"10.4103\/0019-5154.190129","article-title":"Hyaline fibromatosis syndrome: a rare inherited disorder","volume":"61","author":"Mantri","year":"2016","journal-title":"Indian J Dermatol"},{"key":"2025082802082131000_15.4.e248447.2","doi-asserted-by":"crossref","DOI":"10.1002\/mgg3.1203","article-title":"Clinical aspects of hyaline fibromatosis syndrome and identification of a novel mutation","volume":"8","author":"H\u00e4rter","year":"2020","journal-title":"Mol Genet Genomic Med"},{"key":"2025082802082131000_15.4.e248447.3","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1002\/ajmg.a.35228","article-title":"Identification of 2 novel ANTXR2 mutations in patients with hyaline fibromatosis syndrome and proposal of a modified grading system","volume":"158A","author":"Denadai","year":"2012","journal-title":"Am J Med Genet A"},{"key":"2025082802082131000_15.4.e248447.4","doi-asserted-by":"crossref","DOI":"10.4103\/ccd.ccd_117_18","article-title":"Juvenile hyaline fibromatosis","volume":"9","author":"Karande","year":"2018","journal-title":"Contemp Clin Dent"},{"key":"2025082802082131000_15.4.e248447.5","unstructured":"Al Kaissi A , Hilmi M , Betadolova Z . 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