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First investigational studies showed high-titre positive antinuclear antibodies, extractable nuclear antibodies and anti-Sj\u00f6gren's-syndrome-related antigen a autoantibodies (anti-SSA), and mild pericardial effusion and aortic regurgitation, but without meeting criteria for systemic lupus erythematosus. She had maxillary sinusitis that did not resolve with antibiotics. Further study displayed elevated calprotectin in faeces. After normal abdominal ultrasound and CT, an intestinal MRI showed thickening of the terminal ileum, orienting towards an inflammatory bowel disease. A colonoscopy showed only minor macroscopic changes. A PET\u2013CT scan was finally requested, which exhibited a diffuse increase in metabolism in the wall of the thoracic and abdominal aortas, suggesting Takayasu\u2019s arteritis.<\/jats:p>","DOI":"10.1136\/bcr-2021-248472","type":"journal-article","created":{"date-parts":[[2022,4,12]],"date-time":"2022-04-12T12:50:36Z","timestamp":1649767836000},"page":"e248472","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Takayasu\u2019s arteritis in an adolescent with fever of unknown origin: the contribution of PET\u2013CT in the diagnosis"],"prefix":"10.1136","volume":"15","author":[{"given":"Lourdes","family":"Fuentes Dom\u00ednguez","sequence":"first","affiliation":[{"name":"Paediatrics, Hospital Universitario de M\u00f3stoles, Mostoles, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2163-3953","authenticated-orcid":false,"given":"\u00c1urea","family":"Cervera Bravo","sequence":"additional","affiliation":[{"name":"Paediatrics, Hospital Universitario de M\u00f3stoles, Mostoles, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Candida","family":"Paniagua Correa","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, Hospital Universitario de Getafe, Getafe, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,4,12]]},"reference":[{"key":"2025082802203870000_15.4.e248472.1","unstructured":"Castellano Cuesta JA , Vela Casasempere P , Takayasu Ade . 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