{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T22:46:45Z","timestamp":1774478805607,"version":"3.50.1"},"reference-count":21,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,4,29]]},"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p>Lymphoedema is a chronic debilitating condition characterised by diffuse swelling caused by lymphatic obstruction. The secondary form of lymphoedema is more common than the primary form. Untreated filariasis remains an important cause of lymphoedema in developing countries. The most common complication of chronic lymphoedema is cellulitis. It is also a risk factor for the development of neoplasms such as lymphangiosarcoma, squamous cell carcinoma, melanoma, lymphoma and malignant fibrous histiocytoma. We report a case of a woman in her 60s who developed squamous cell carcinoma in the background of chronic lymphoedema.<\/jats:p>","DOI":"10.1136\/bcr-2021-248543","type":"journal-article","created":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T12:54:50Z","timestamp":1653310490000},"page":"e248543","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Chronic lymphoedema: a nidus for squamous cell carcinoma"],"prefix":"10.1136","volume":"15","author":[{"given":"Shrea","family":"Gulati","sequence":"first","affiliation":[{"name":"Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9924-853X","authenticated-orcid":false,"given":"Sheragaru Hanumanthappa","family":"Chandrashekhara","sequence":"additional","affiliation":[{"name":"Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Bhoriwal","sequence":"additional","affiliation":[{"name":"Surgical Oncology, AIIMS, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Snehal Ishwar","family":"Kose","sequence":"additional","affiliation":[{"name":"Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,5,10]]},"reference":[{"key":"2025082801082736000_15.5.e248543.1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.revmed.2016.07.005","article-title":"[Lymphedema: From diagnosis to treatment]","volume":"38","author":"Vignes","year":"2017","journal-title":"Rev Med Interne"},{"key":"2025082801082736000_15.5.e248543.2","first-page":"2124","article-title":"[Primary lymphedema]","volume":"13","author":"Depairon","year":"2017","journal-title":"Rev Med Suisse"},{"key":"2025082801082736000_15.5.e248543.3","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(02)00734-9"},{"key":"2025082801082736000_15.5.e248543.4","first-page":"2050313X1349650","article-title":"Squamous cell carcinoma arising from congenital lymphedema","volume":"1","author":"Parthiban","year":"2013","journal-title":"SAGE Open Med Case Rep"},{"key":"2025082801082736000_15.5.e248543.5","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1111\/j.1365-2133.1997.tb14950.x","article-title":"Squamous cell carcinoma arising in chronic lymphoedema","volume":"136","author":"Lister","year":"1997","journal-title":"Br J Dermatol"},{"key":"2025082801082736000_15.5.e248543.6","doi-asserted-by":"crossref","unstructured":"Gloviczki . 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