{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:04:52Z","timestamp":1756339492481,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"6","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,5,20]]},"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:p>A Caucasian female patient in her 90s was referred to the department of plastic and reconstructive surgery for surgical removal of a large invasive squamous cell carcinoma on the anterior chest wall. A skin biopsy prior to the referral indicated that the tumour was moderately differentiated. The patient suffered from severe congestive heart failure with a mechanical valve prosthesis and atrial fibrillation, and was therefore treated with anticoagulants. Hence, a surgical procedure would be hazardous. Therefore, other treatment options were considered. The principal aim was to reduce the amount of tumour tissue to an appropriate size suitable for later excision with primary wound closure. After interdisciplinary discussions, curettage and electrodessication combined with photodynamic therapy was judged the best alternative treatment in this case. At the 1.5\u2009years follow-up after the intervention there was no indication for further surgery. The patient was at that stage content with the treatment and its outcome.<\/jats:p>","DOI":"10.1136\/bcr-2021-248588","type":"journal-article","created":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T12:10:48Z","timestamp":1654085448000},"page":"e248588","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Curettage and electrodessication combined with photodynamic therapy in the treatment of large squamous cell carcinomas in unfit and frail patients"],"prefix":"10.1136","volume":"15","author":[{"given":"Henrik","family":"Luu","sequence":"first","affiliation":[{"name":"Department of Dermatology, Department of Clinical Sciences Malmo, Lund University, Sk\u00e5ne University Hospital, Malmo, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e5ns","family":"Cornefjord","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Department of Clinical Sciences Malmo, Lund University, Sk\u00e5ne University Hospital, Malmo, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c5ke","family":"Svensson","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Department of Clinical Sciences Malmo, Lund University, Sk\u00e5ne University Hospital, Malmo, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry","family":"Svensson","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Department of Clinical Sciences Malmo, Lund University, Sk\u00e5ne University Hospital, Malmo, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,6,1]]},"reference":[{"key":"2025082708154758000_15.6.e248588.1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.hoc.2018.08.001","article-title":"Cutaneous squamous cell carcinoma","volume":"33","author":"Waldman","year":"2019","journal-title":"Hematol Oncol Clin North Am"},{"key":"2025082708154758000_15.6.e248588.2","unstructured":"Swedish National Board of Health and Welfare Data from . Swedish national board of health and welfare. statistical database, cancer, 2021. Available: https:\/\/sdb.socialstyrelsen.se\/if_can\/val.aspx"},{"key":"2025082708154758000_15.6.e248588.3","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.det.2019.05.002","article-title":"Review and update on evidence-based surgical treatment recommendations for nonmelanoma skin cancer","volume":"37","author":"Shelton","year":"2019","journal-title":"Dermatol Clin"},{"key":"2025082708154758000_15.6.e248588.4","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1046\/j.1440-0960.2000.00383.x","article-title":"Curettage, electrosurgery and skin cancer","volume":"41","author":"Sheridan","year":"2000","journal-title":"Australas J Dermatol"},{"key":"2025082708154758000_15.6.e248588.5","unstructured":"Bjarke T . Basaliom och Skivepitelcancer: Behandling med curretage-electrodesiccation. Stockholm, Sweden: Essex l\u00e4kemedel, 1984: 1\u201379."},{"key":"2025082708154758000_15.6.e248588.6","doi-asserted-by":"crossref","unstructured":"Gold M . Photodynamic therapy in dermatology. New York, NY, USA: Springer Science + Business Media, 2011: 1\u2013205.","DOI":"10.1007\/978-1-4419-1298-5_1"},{"key":"2025082708154758000_15.6.e248588.7","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1159\/000366539","article-title":"Dermoscopy of actinic keratosis, intraepidermal carcinoma and squamous cell carcinoma","volume":"46","author":"Zalaudek","year":"2015","journal-title":"Curr Probl Dermatol"},{"key":"2025082708154758000_15.6.e248588.8","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.ejca.2020.01.007","article-title":"European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: part 1. epidemiology, diagnostics and prevention","volume":"128","author":"Stratigos","year":"2020","journal-title":"Eur J Cancer"},{"key":"2025082708154758000_15.6.e248588.9","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.jaad.2017.10.007","article-title":"Guidelines of care for the management of cutaneous squamous cell carcinoma","volume":"78","author":"Kim","year":"2018","journal-title":"J Am Acad Dermatol"},{"key":"2025082708154758000_15.6.e248588.10","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f6153"},{"key":"2025082708154758000_15.6.e248588.11","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ejca.2020.01.008","article-title":"European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: Part 2. treatment","volume":"128","author":"Stratigos","year":"2020","journal-title":"Eur J Cancer"},{"key":"2025082708154758000_15.6.e248588.12","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.pdpdt.2018.09.009","article-title":"Photodynamic therapy for Bowen's disease (squamous cell carcinoma in situ) current review and update","volume":"24","author":"O'Connell","year":"2018","journal-title":"Photodiagnosis Photodyn Ther"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-248588","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:15:57Z","timestamp":1756307757000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-248588"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":12,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2022,6,1]]},"published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1136\/bcr-2021-248588"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-248588","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2022,6]]}}}