{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:40:05Z","timestamp":1756374005791,"version":"3.44.0"},"reference-count":13,"publisher":"BMJ","issue":"8","funder":[{"DOI":"10.13039\/501100005809","name":"Hyderabad Eye Research Foundation","doi-asserted-by":"publisher","award":["LEC-BHR-R-12-21-799"],"award-info":[{"award-number":["LEC-BHR-R-12-21-799"]}],"id":[{"id":"10.13039\/501100005809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,8,11]]},"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:p>A teenage boy presented to the clinic complaining of poor vision in both eyes. His best-corrected visual acuity was 20\/25. The slit lamp examination revealed vertically oval corneas, crescentic peripheral inferior corneal thinning and ectasia in both eyes. Corneal topography showed against-the-rule astigmatism with mean keratometry (Km) of 45.1 and 45.2 dioptres in the right and left eyes, respectively. High-resolution optical coherence tomography corroborated the clinical findings, and the patient was diagnosed with pellucid marginal corneal degeneration (PMD). Collagen cross-linking was performed in the right eye. Left eye cross-linking is awaited. Although PMD is typically seen in middle-aged (third-fourth decade) patients, it can also occur at earlier ages. Collagen cross-linking can be considered to prevent the progression of the condition.<\/jats:p>","DOI":"10.1136\/bcr-2021-248599","type":"journal-article","created":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T11:16:11Z","timestamp":1660907771000},"page":"e248599","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Pellucid marginal corneal degeneration in a teenager"],"prefix":"10.1136","volume":"15","author":[{"given":"Gopikrishna I","family":"Nelapatla","sequence":"first","affiliation":[{"name":"LV Prasad Eye Institute, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6195-0024","authenticated-orcid":false,"given":"Sunita","family":"Chaurasia","sequence":"additional","affiliation":[{"name":"Cornea and Anterior Segment, LV Prasad Eye Institute, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,8,19]]},"reference":[{"key":"2025082802081742000_15.8.e248599.1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1978.03910060051009"},{"key":"2025082802081742000_15.8.e248599.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2010.11.007"},{"key":"2025082802081742000_15.8.e248599.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2003.09.035"},{"key":"2025082802081742000_15.8.e248599.4","doi-asserted-by":"crossref","first-page":"3488","DOI":"10.4103\/ijo.IJO_553_21","article-title":"Clinical profile and demographic distribution of pellucid marginal corneal degeneration in India: a study of 559 patients","volume":"69","author":"Das","year":"2021","journal-title":"Indian J Ophthalmol"},{"key":"2025082802081742000_15.8.e248599.5","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1016\/S0886-3350(02)02038-2","article-title":"Intracorneal rings for the correction of pellucid marginal degeneration","volume":"29","author":"Rodriguez-Prats","year":"2003","journal-title":"J Cataract Refract Surg"},{"key":"2025082802081742000_15.8.e248599.6","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/j.1444-0938.2004.tb03172.x","article-title":"Pellucid marginal degeneration and scleroderma","volume":"87","author":"Sii","year":"2004","journal-title":"Clin Exp Optom"},{"key":"2025082802081742000_15.8.e248599.7","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0002-9394(98)00349-3","article-title":"Corneal topography in asymptomatic family members of a patient with pellucid marginal degeneration","volume":"127","author":"Santo","year":"1999","journal-title":"Am J Ophthalmol"},{"key":"2025082802081742000_15.8.e248599.8","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1997.01100150276023"},{"key":"2025082802081742000_15.8.e248599.9","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s10384-016-0462-0","article-title":"National survey of pellucid marginal corneal degeneration in Japan","volume":"60","author":"Shimazaki","year":"2016","journal-title":"Jpn J Ophthalmol"},{"key":"2025082802081742000_15.8.e248599.10","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.sjopt.2012.04.001","article-title":"Deep anterior lamellar keratoplasty for pellucid marginal degeneration","volume":"27","author":"Al-Torbak","year":"2013","journal-title":"Saudi J Ophthalmol"},{"key":"2025082802081742000_15.8.e248599.11","doi-asserted-by":"crossref","first-page":"375","DOI":"10.3928\/1081597X-20100114-03","article-title":"Corneal collagen cross-linking with riboflavin and UVA irradiation in pellucid marginal degeneration","volume":"26","author":"Spadea","year":"2010","journal-title":"J Refract Surg"},{"key":"2025082802081742000_15.8.e248599.12","doi-asserted-by":"crossref","first-page":"367","DOI":"10.4103\/0301-4738.109523","article-title":"Collagen cross-linking in the treatment of pellucid marginal degeneration","volume":"62","author":"Hassan","year":"2014","journal-title":"Indian J Ophthalmol"},{"key":"2025082802081742000_15.8.e248599.13","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e318269059b"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-248599","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:08:22Z","timestamp":1756372102000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-248599"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":13,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2022,8,19]]},"published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1136\/bcr-2021-248599"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-248599","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2022,8]]}}}