{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:04:43Z","timestamp":1756339483436,"version":"3.44.0"},"reference-count":16,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,5,20]]},"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:p>IgA vasculitis is a rare systemic vasculitis in adults, frequently more severe than in paediatric age. It manifests with cutaneous, articular, gastrointestinal and renal involvement.<\/jats:p>\n               <jats:p>We present a case of a man in his 40s diagnosed with IgA vasculitis with cutaneous, joint, gastrointestinal and renal disease. Significant proteinuria and renal biopsy findings demonstrating crescentic glomerulonephritis led to the onset of early immunosuppression with corticoid and cyclophosphamide. This case report reflects a case of more severe renal impairment due to IgA vasculitis with good outcome with the chosen therapy. The findings in the renal biopsy after treatment supported the good response to the chosen immunosuppression.<\/jats:p>","DOI":"10.1136\/bcr-2021-248686","type":"journal-article","created":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T11:11:05Z","timestamp":1654600265000},"page":"e248686","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["IgA vasculitis with severe renal manifestation"],"prefix":"10.1136","volume":"15","author":[{"given":"Joana","family":"Marques Dias","sequence":"first","affiliation":[{"name":"Internal Medicine, Hospital Beatriz Angelo, Loures, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta Azevedo","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Internal Medicine, Hospital Beatriz Angelo, Loures, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Grilo","sequence":"additional","affiliation":[{"name":"Internal Medicine, Hospital Beatriz Angelo, Loures, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando Martos","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Internal Medicine, Hospital Beatriz Angelo, Loures, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,6,7]]},"reference":[{"key":"2025082707445071000_15.6.e248686.1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e32835d8e2a"},{"key":"2025082707445071000_15.6.e248686.2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000013883.99976.22"},{"key":"2025082707445071000_15.6.e248686.3","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1002\/art.40178","article-title":"Characteristics and management of IgA vasculitis (Henoch-Sch\u00f6nlein) in adults: data from 260 patients included in a French multicenter retrospective survey","volume":"69","author":"Audemard-Verger","year":"2017","journal-title":"Arthritis Rheumatol"},{"key":"2025082707445071000_15.6.e248686.4","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s13075-016-0959-4","article-title":"Iga vasculitis in adults: the performance of the EULAR\/PRINTO\/PRES classification criteria in adults","volume":"18","author":"Ho\u010devar","year":"2016","journal-title":"Arthritis Res Ther"},{"key":"2025082707445071000_15.6.e248686.5","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfv095"},{"key":"2025082707445071000_15.6.e248686.6","first-page":"S26","article-title":"Henoch-Sch\u00f6nlein's purpura in adults versus children\/adolescents: a comparative study","volume":"24","author":"Uppal","year":"2006","journal-title":"Clin Exp Rheumatol"},{"key":"2025082707445071000_15.6.e248686.7","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2011.16"},{"key":"2025082707445071000_15.6.e248686.8","doi-asserted-by":"crossref","unstructured":"Pillebout E . Clinical medicine IgA vasculitis and IgA nephropathy: same disease? 2021.","DOI":"10.3390\/jcm10112310"},{"key":"2025082707445071000_15.6.e248686.9","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2005020134"},{"key":"2025082707445071000_15.6.e248686.10","unstructured":"Gupta S , Das P . 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