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He underwent an uncomplicated left laparoscopic cytoreductive nephrectomy and made a satisfactory recovery. To our knowledge, this is the first reported case of primary mRCC presenting with digital soft tissue metastasis. Cytoreductive nephrectomy with metastasectomy is the preferred management for mRCC where feasible. For unfavourable mRCC cases, first-line systemic therapy is indicated. Adjuvant systemic therapy in mRCC is currently limited to clinical trials, though promising data emerging on the use of pembrolizumab may herald a future shift in practice.<\/jats:p>","DOI":"10.1136\/bcr-2021-248718","type":"journal-article","created":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T13:44:06Z","timestamp":1653313446000},"page":"e248718","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Isolated soft tissue mass of the finger as the first presentation of oligometastatic renal cell carcinoma"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0598-9973","authenticated-orcid":false,"given":"David T","family":"Hopkins","sequence":"first","affiliation":[{"name":"Department of Urology, Saint James's Hospital, Dublin, Ireland"},{"name":"Department of Surgery, Trinity College Dublin School of Medicine, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darragh","family":"Waters","sequence":"additional","affiliation":[{"name":"Department of Urology, Saint James's Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3437-744X","authenticated-orcid":false,"given":"Rustom P","family":"Manecksha","sequence":"additional","affiliation":[{"name":"Department of Urology, Saint James's Hospital, Dublin, Ireland"},{"name":"Department of Surgery, Trinity College Dublin School of Medicine, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas H","family":"Lynch","sequence":"additional","affiliation":[{"name":"Department of Urology, Saint James's Hospital, Dublin, Ireland"},{"name":"Department of Surgery, Trinity College Dublin School of Medicine, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,5,17]]},"reference":[{"key":"2025082707242663000_15.5.e248718.1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nrdp.2017.9","article-title":"Renal cell carcinoma","volume":"3","author":"Hsieh","year":"2017","journal-title":"Nat Rev Dis Primers"},{"key":"2025082707242663000_15.5.e248718.2","doi-asserted-by":"publisher","DOI":"10.1016\/J.EJCA.2018.07.005"},{"key":"2025082707242663000_15.5.e248718.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(97)00506-2"},{"key":"2025082707242663000_15.5.e248718.4","unstructured":"Ljungberg B , Albiges L , Bensalah K . 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