{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T02:55:36Z","timestamp":1772852136200,"version":"3.50.1"},"reference-count":4,"publisher":"BMJ","issue":"5","license":[{"start":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T00:00:00Z","timestamp":1651795200000},"content-version":"unspecified","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,4,5]]},"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p>A woman in her 20s presented with progressive weakness of her left arm and leg, slurred speech and swallowing difficulties. The clinical presentation and neurophysiological tests were consistent with motor neuron disease. She was referred to the regional ventilation unit for respiratory muscle function testing. This confirmed restrictive spirometry and borderline sniff nasal inspiratory pressure and cough peak expiratory flow. Three years later, she presented with an unplanned pregnancy and expressed the wish to continue the pregnancy to term. She was monitored throughout pregnancy with interval respiratory muscle testing and was reviewed in the high-risk pregnancy anaesthetic clinic. She was also closely monitored by the obstetrics and gynaecology team. A multidisciplinary team meeting between all stakeholders agreed on caesarean section delivery at 34 weeks. The pregnancy and the delivery were without complications; the baby was healthy and both mother and baby remain well to date.<\/jats:p>","DOI":"10.1136\/bcr-2022-248872","type":"journal-article","created":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T12:17:29Z","timestamp":1651839449000},"page":"e248872","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["A case of successful pregnancy managed in a patient living with Motor Neurone Disease for more than 3 years"],"prefix":"10.1136","volume":"15","author":[{"given":"Abdisamad","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Mowat","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naomi","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naveed","family":"Mustfa","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,5,6]]},"reference":[{"key":"2025082700333824000_15.5.e248872.1","doi-asserted-by":"crossref","first-page":"745-51","DOI":"10.1111\/j.1468-1331.2009.02586.x","article-title":"Incidence and lifetime risk of motor neuron disease in the United Kingdom: a population-based study","volume":"16","author":"Alonso","year":"2009","journal-title":"Eur J Neurol"},{"key":"2025082700333824000_15.5.e248872.2","doi-asserted-by":"crossref","first-page":"483","DOI":"10.3109\/17482960802578365","article-title":"Two consecutive pregnancies in early and late stage of amyotrophic lateral sclerosis","volume":"10","author":"Sarafov","year":"2009","journal-title":"Amyotroph Lateral Scler"},{"key":"2025082700333824000_15.5.e248872.3","doi-asserted-by":"publisher","DOI":"10.1183\/20734735.008615"},{"key":"2025082700333824000_15.5.e248872.4","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1164\/ajrccm\/137.3.668","article-title":"Rib cage and abdominal volume displacements during breathing in pregnancy","volume":"137","author":"Gilroy","year":"1988","journal-title":"Am Rev Respir Dis"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-248872","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T07:33:49Z","timestamp":1756280029000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-248872"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":4,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,5,6]]},"published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1136\/bcr-2022-248872"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-248872","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5]]}}}